Literature DB >> 6235745

Safety profile: fifteen years of clinical experience with ibuprofen.

G L Royer, C E Seckman, I R Welshman.   

Abstract

Since its introduction in the United States in 1974, ibuprofen (Motrin, Upjohn) has been shown to be safe and effective for the treatment of pain, dysmenorrhea, inflammation, and fever. A careful review of pre-registration and postmarketing data from both patients and normal subjects clearly indicates ibuprofen's remarkable safety profile compared with that of aspirin and other commonly prescribed nonsteroidal anti-inflammatory agents. Continued safety can be anticipated on the basis of the past 15 years of review experience.

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Year:  1984        PMID: 6235745     DOI: 10.1016/s0002-9343(84)80015-7

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  7 in total

Review 1.  Toxic effects of nonsteroidal anti-inflammatory drugs in overdose. An overview of recent evidence on clinical effects and dose-response relationships.

Authors:  S C Smolinske; A H Hall; S A Vandenberg; D G Spoerke; P V McBride
Journal:  Drug Saf       Date:  1990 Jul-Aug       Impact factor: 5.606

2.  Adverse effects of a 10-day course of ibuprofen in Holstein calves.

Authors:  P Walsh; F R Carvallo Chaigneau; M Anderson; N Behrens; H McEligot; B Gunnarson; L J Gershwin
Journal:  J Vet Pharmacol Ther       Date:  2016-02-14       Impact factor: 1.786

Review 3.  Nonsteroidal anti-inflammatory drug-induced hepatic disorders. Incidence and prevention.

Authors:  A V Manoukian; J L Carson
Journal:  Drug Saf       Date:  1996-07       Impact factor: 5.606

4.  Effects of ibuprofen on cognition and NMDA receptor subunit expression across aging.

Authors:  Alejandra Márquez Loza; Valerie Elias; Carmen P Wong; Emily Ho; Michelle Bermudez; Kathy R Magnusson
Journal:  Neuroscience       Date:  2017-01-03       Impact factor: 3.590

5.  Use of non-steroidal anti-inflammatory drugs and risk of Parkinson's disease: nested case-control study.

Authors:  Jane A Driver; Giancarlo Logroscino; Linda Lu; J Michael Gaziano; Tobias Kurth
Journal:  BMJ       Date:  2011-01-20

6.  A randomized controlled trial of a combination of antiviral and nonsteroidal anti-inflammatory treatment in a bovine model of respiratory syncytial virus infection.

Authors:  Paul Walsh; Maxim Lebedev; Heather McEligot; Victoria Mutua; Heejung Bang; Laurel J Gershwin
Journal:  PLoS One       Date:  2020-03-12       Impact factor: 3.240

7.  Analysis of lung transcriptome in calves infected with Bovine Respiratory Syncytial Virus and treated with antiviral and/or cyclooxygenase inhibitor.

Authors:  Maxim Lebedev; Heather A McEligot; Victoria N Mutua; Paul Walsh; Francisco R Carvallo Chaigneau; Laurel J Gershwin
Journal:  PLoS One       Date:  2021-02-18       Impact factor: 3.240

  7 in total

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