Literature DB >> 6234889

A protein inhibitor of phosphofructokinase from the mucosa of rat small intestine. A mechanism for the regulation of glycolysis that is independent of glucose.

G L Kellett, J P Robertson.   

Abstract

A protein inhibitor of phosphofructokinase was detected by the chromatography on Sephadex G-100 of crude mucosal extracts prepared from the small intestine of starved rats. Addition of the protein inhibitor to extracts from fed rats increased the K0.5 of phosphofructokinase for fructose 6-phosphate to that for starved rats. The protein inhibitor provides a mechanism for the hormonal regulation of glycolysis independently of glucose supply.

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Year:  1984        PMID： 6234889      PMCID： PMC1153666          DOI： 10.1042/bj2200601

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  12 in total

1.  The isolation and characterization of phosphofructokinase from the epithelial cells of rat small intestine.

Authors:  S M Khoja; N L Beach; G L Kellett
Journal:  Biochem J       Date:  1983-05-01       Impact factor: 3.857

2.  Fructose 2,6-bisphosphate 2 years after its discovery.

Authors:  H G Hers; E Van Schaftingen
Journal:  Biochem J       Date:  1982-07-15       Impact factor: 3.857

3.  Changes in the concentration of activation factor for phosphofructokinase in hepatocytes in response to glucose and glucagon.

Authors:  C S Richards; K Uyeda
Journal:  Biochem Biophys Res Commun       Date:  1980-12-31       Impact factor: 3.575

4.  Respiratory fuels and nitrogen metabolism in vivo in small intestine of fed rats. Quantitative importance of glutamine, glutamate, and aspartate.

Authors:  H G Windmueller; A E Spaeth
Journal:  J Biol Chem       Date:  1980-01-10       Impact factor: 5.157

5.  Fructose 2,6-bisphosphate. Hormonal regulation and mechanism of its formation in liver.

Authors:  L Hue; P F Blackmore; J H Exton
Journal:  J Biol Chem       Date:  1981-09-10       Impact factor: 5.157

6.  The effect of starvation on the control of phosphofructokinase activity in the epithelial cells of the rat small intestine.

Authors:  A Jamal; G L Kellett
Journal:  Biochem J       Date:  1983-01-15       Impact factor: 3.857

7.  Fructose 2,6-bisphosphate. A new activator of phosphofructokinase.

Authors:  S J Pilkis; M R El-Maghrabi; J Pilkis; T H Claus; D A Cumming
Journal:  J Biol Chem       Date:  1981-04-10       Impact factor: 5.157

8.  The effect of natural and synthetic D-fructose 2,6-bisphosphate on the regulatory kinetic properties of liver and muscle phosphofructokinases.

Authors:  K Uyeda; E Furuya; L J Luby
Journal:  J Biol Chem       Date:  1981-08-25       Impact factor: 5.157

9.  Fructose 2,6-bisphosphate, the probably structure of the glucose- and glucagon-sensitive stimulator of phosphofructokinase.

Authors:  E Van Schaftingen; L Hue; H G Hers
Journal:  Biochem J       Date:  1980-12-15       Impact factor: 3.857

10.  Control of the fructose-6-phosphate/fructose 1,6-bisphosphate cycle in isolated hepatocytes by glucose and glucagon. Role of a low-molecular-weight stimulator of phosphofructokinase.

Authors:  E Van Schaftingen; L Hue; H G Hers
Journal:  Biochem J       Date:  1980-12-15       Impact factor: 3.857
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  1 in total

1.  Beta-adrenergic agents increase the phosphorylation of phosphofructokinase in isolated rat epididymal white adipose tissue.

Authors:  E M Sale; R M Denton
Journal:  Biochem J       Date:  1985-12-15       Impact factor: 3.857
  1 in total

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