| Literature DB >> 6234402 |
A P Autor, A C Bonham, R L Thies.
Abstract
Superoxide dismutase and catalase, which catalytically remove O-2 and H2O2, respectively, each separately protected cultured pulmonary artery endothelial cells from loss of membrane integrity after exposure to oxygen radicals generated either cellularly (polymorphonuclear leukocytes) or chemically (dihydroxyfumarate). Nicotinamide, a precursor of nicotinamide-adenine dinucleotide (NAD) and an inhibitor of ADP-ribose synthetase, also protected cultured endothelial cells from loss of membrane integrity in a concentration-dependent manner after exposure to DHF.Entities:
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Year: 1984 PMID： 6234402 DOI： 10.1080/15287398409530505
Source DB: PubMed Journal: J Toxicol Environ Health ISSN： 0098-4108