Literature DB >> 6234378

Serum anticonvulsant concentrations and the risk of drug induced skin eruptions.

D Chadwick, M D Shaw, P Foy, M D Rawlins, D M Turnbull.   

Abstract

In two prospective studies of anticonvulsant therapy there was a high incidence of drug-induced skin reactions to phenytoin (7%) and carbamazepine (16.6%). High initial serum concentrations of these drugs appeared to be a factor influencing the occurrence of such skin reactions.

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Year:  1984        PMID： 6234378      PMCID： PMC1027864          DOI： 10.1136/jnnp.47.6.642

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  5 in total

Review 1.  The side-effects of carbamazepine.

Authors:  J J Gayford; T H Redpath
Journal:  Proc R Soc Med       Date:  1969-06

2.  [Plasma concentrations after injection or infusion of phenytoin (author's transl)].

Authors:  D Schmidt; A Vogel
Journal:  Klin Wochenschr       Date:  1977-03-01

3.  The incidence of postoperative seizures.

Authors:  P M Foy; G P Copeland; M D Shaw
Journal:  Acta Neurochir (Wien)       Date:  1981       Impact factor: 2.216

4.  A comparison of phenytoin and valproate in previously untreated adult epileptic patients.

Authors:  D M Turnbull; M D Rawlins; D Weightman; D W Chadwick
Journal:  J Neurol Neurosurg Psychiatry       Date:  1982-01       Impact factor: 10.154

5.  Loading and conventional dose therapy with phenytoin in children: kinetic profile of parent drug and main metabolite in plasma.

Authors:  J T Wilson; B Höjer; A Rane
Journal:  Clin Pharmacol Ther       Date:  1976-07       Impact factor: 6.875
  5 in total
  23 in total

Review 1.  Is generic prescribing acceptable in epilepsy?

Authors:  F M Besag
Journal:  Drug Saf       Date:  2000-09       Impact factor: 5.606

2.  Do prophylactic anticonvulsant drugs alter the pattern of seizures after craniotomy?

Authors:  P M Foy; D W Chadwick; N Rajgopalan; A L Johnson; M D Shaw
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-09       Impact factor: 10.154

Review 3.  Idiosyncratic drug reactions: a mechanistic evaluation of risk factors.

Authors:  B K Park; M Pirmohamed; N R Kitteringham
Journal:  Br J Clin Pharmacol       Date:  1992-11       Impact factor: 4.335

4.  Rash in four patients with brain tumor-related epilepsy in monotherapy with oxcarbazepine, during radiotherapy.

Authors:  M Maschio; L Dinapoli; A Vidiri; Paola Muti
Journal:  J Neurol       Date:  2010-07-08       Impact factor: 4.849

5.  Stevens-Johnson syndrome and toxic epidermal necrolysis with antiepileptic drugs: An analysis of the US Food and Drug Administration Adverse Event Reporting System.

Authors:  Eric P Borrelli; Erica Y Lee; Andrew M Descoteaux; Stephen J Kogut; Aisling R Caffrey
Journal:  Epilepsia       Date:  2018-11-05       Impact factor: 5.864

Review 6.  Anticonvulsant hypersensitivity syndrome: incidence, prevention and management.

Authors:  S R Knowles; L E Shapiro; N H Shear
Journal:  Drug Saf       Date:  1999-12       Impact factor: 5.606

Review 7.  Genetic factors in the predisposition to drug-induced hypersensitivity reactions.

Authors:  Munir Pirmohamed
Journal:  AAPS J       Date:  2006-02-03       Impact factor: 4.009

8.  Pharmacokinetics and pharmacodynamics of tucaresol, an antisickling agent, in healthy volunteers.

Authors:  P E Rolan; A J Mercer; R Wootton; J Posner
Journal:  Br J Clin Pharmacol       Date:  1995-04       Impact factor: 4.335

Review 9.  CNS adverse events associated with antiepileptic drugs.

Authors:  Gina M Kennedy; Samden D Lhatoo
Journal:  CNS Drugs       Date:  2008       Impact factor: 5.749

10.  Carbamazepine-hypersensitivity: assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine.

Authors:  M Pirmohamed; A Graham; P Roberts; D Smith; D Chadwick; A M Breckenridge; B K Park
Journal:  Br J Clin Pharmacol       Date:  1991-12       Impact factor: 4.335
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