| Literature DB >> 6234163 |
Abstract
Comparison of the amino acid sequences of 13 procaryotic regulatory proteins, including the products of genes crp (catabolite activator protein; CAP), lacI, galR , lexA, lysR, araC, trpR, and tnpR of Escherichia coli, of genes cI, cII and cro of phage lambda, cro of phage 434, and c2 of phage P22, has revealed two regions of homology. The sites of action of these proteins also share common features in their DNA sequence. Taking into account the models proposed for the lambda repressors, cro and cI, and for CAP, a general type of DNA-protein interaction is suggested.Entities:
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Year: 1982 PMID: 6234163 PMCID: PMC553092 DOI: 10.1002/j.1460-2075.1982.tb01213.x
Source DB: PubMed Journal: EMBO J ISSN: 0261-4189 Impact factor: 11.598