Literature DB >> 6233972

Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells.

A Rodriguez-Pena, E Rozengurt.   

Abstract

Treatment of intact 3T3 cells with biologically active phorbol esters causes a progressive decline in the total activity of Ca2+-sensitive, phospholipid-dependent protein kinase (protein kinase C) measured in cell-free, detergent-solubilized, extracts. The effect is dose-dependent and reversible; protein kinase C activity reappears when the phorbol esters are removed from the medium.

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Year:  1984        PMID： 6233972     DOI： 10.1016/s0006-291x(84)80213-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  131 in total

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