Literature DB >> 6232493

Monoclonal antibodies against antigens of the human platelet surface: preparation and properties.

H Zola, P J McNamara, I G Beckman, D A Brooks, P J Macardle, J Bradley, K Goodall, J Skinner, R Collins, M C Berndt.   

Abstract

Three monoclonal antibodies, FMC24, 25 and 27, reactive with human platelets, are described. In normal blood the 3 antibodies are specific for platelets, but FMC27 reacts with leukemic blast cells in a proportion of acute leukemias. FMC25 precipitates the platelet membrane glycoprotein lb and a glycoprotein of molecular weight 22,000. The antibodies show different effects on platelet aggregation.

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Year:  1984        PMID: 6232493     DOI: 10.3109/00313028409067914

Source DB:  PubMed          Journal:  Pathology        ISSN: 0031-3025            Impact factor:   5.306


  4 in total

1.  The phenotype of L-CFU and its correlation with the immunological characteristics of the blast cell population in AML.

Authors:  M C del Cañizo; J Almeida; J F San Miguel; A Orfao; M Gonzalez; A Lopez Borrasca
Journal:  Ann Hematol       Date:  1994-05       Impact factor: 3.673

2.  The nature of blast cells in myelodysplastic syndromes evolving to acute leukaemia.

Authors:  J F San Miguel; M González; M C Cañizo; J P Anta; J Hernández; F Ortega; L Borrasca
Journal:  Blut       Date:  1986-06

3.  Method for the simultaneous labelling of terminal deoxynucleotidyl transferase (TdT) and membrane antigens.

Authors:  J Tavares de Castro; J F San Miguel; J Soler; D Catovsky
Journal:  J Clin Pathol       Date:  1984-06       Impact factor: 3.411

4.  Induction of platelet-derived growth factor gene expression during megakaryoblastic and monocytic differentiation of human leukemia cell lines.

Authors:  R Alitalo; L C Andersson; C Betsholtz; K Nilsson; B Westermark; C H Heldin; K Alitalo
Journal:  EMBO J       Date:  1987-05       Impact factor: 11.598

  4 in total

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