Occupational exposure to hepatitis B virus. Analysis of indications for hepatitis B vaccine.

This retrospective study was undertaken to determine the incidence of acute and chronic morbidity due to hepatitis B infection among employees of an institution for the mentally retarded. Based on a review of medical records, surveillance data, and serologic testing, we found no evidence of excess morbidity among 2,000 employees in a 10-year period. Hepatitis B vaccination is neither warranted nor presently cost-effective for most client-care personnel.