Literature DB >> 6230988

In vitro activities of ciprofloxacin, norfloxacin, pipemidic acid, cinoxacin, and nalidixic acid against Chlamydia trachomatis.

F W Heessen, H L Muytjens.   

Abstract

The in vitro activities of five quinolinecarboxylic acids against two laboratory strains of Chlamydia trachomatis were compared. The minimal inhibitory concentrations of nalidixic acid, cinoxacin, and pipemidic acid were all greater than or equal to 50 micrograms/ml; the activity of norfloxacin was intermediate (minimal inhibitory concentration, 8 to 16 micrograms/ml). Ciprofloxacin was the most active of these drugs (minimal inhibitory concentration, 0.5 to 1 microgram/ml).

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Year:  1984        PMID: 6230988      PMCID: PMC185448          DOI: 10.1128/AAC.25.1.123

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  9 in total

1.  In vitro activity of norfloxacin against Chlamydia trachomatis.

Authors:  H Meier-Ewert; G Weil; G Millott
Journal:  Eur J Clin Microbiol       Date:  1983-06       Impact factor: 3.267

2.  Comparative in vitro activity of Mk-0366 and other selected oral antimicrobial agents against Neisseria gonorrhoeae.

Authors:  M Y Khan; Y Siddiqui; R P Gruninger
Journal:  Antimicrob Agents Chemother       Date:  1981-08       Impact factor: 5.191

3.  In vitro activities of thirteen beta-lactam antibiotics against Chlamydia trachomatis.

Authors:  H L Muytjens; F W Heessen
Journal:  Antimicrob Agents Chemother       Date:  1982-09       Impact factor: 5.191

4.  Antimycoplasmal activity of ofloxacin (DL-8280).

Authors:  Y Osada; H Ogawa
Journal:  Antimicrob Agents Chemother       Date:  1983-03       Impact factor: 5.191

5.  The lack of effect of ampicillin plus probenecid given for genital infections with Neisseria gonorrhoeae on associated infections with Chlamydia trachomatis.

Authors:  J D Oriel; G L Ridgway; P Reeve; D C Beckingham; J Owen
Journal:  J Infect Dis       Date:  1976-05       Impact factor: 5.226

6.  Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid.

Authors:  H L Muytjens; J van der Ros-van de Repe; G van Veldhuizen
Journal:  Antimicrob Agents Chemother       Date:  1983-08       Impact factor: 5.191

7.  In vitro activity of ciprofloxacin, norfloxacin and nalidixic acid.

Authors:  A Bauernfeind; C Petermüller
Journal:  Eur J Clin Microbiol       Date:  1983-04       Impact factor: 3.267

8.  In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents.

Authors:  R Wise; J M Andrews; L J Edwards
Journal:  Antimicrob Agents Chemother       Date:  1983-04       Impact factor: 5.191

9.  In vitro antimicrobial activity of rosoxacin against Neisseria gonorrhoeae, Chlamydia trachomatis, and Ureaplasma urealyticum.

Authors:  R A Dobson; J R O'Connor; S A Poulin; R B Kundsin; T F Smith; P E Came
Journal:  Antimicrob Agents Chemother       Date:  1980-11       Impact factor: 5.191

  9 in total
  29 in total

1.  In vitro activity of difloxacin hydrochloride (A-56619), A-56620, and cefixime (CL 284,635; FK 027) against selected genital pathogens.

Authors:  W R Bowie; C E Shaw; D G Chan; J Boyd; W A Black
Journal:  Antimicrob Agents Chemother       Date:  1986-10       Impact factor: 5.191

2.  Norfloxacin in the therapy of uncomplicated gonorrhea.

Authors:  B Romanowski; H Wood; J Draker; M C Tsianco
Journal:  Antimicrob Agents Chemother       Date:  1986-09       Impact factor: 5.191

3.  Comparative trial of single-dose ciprofloxacin and ampicillin plus probenecid for treatment of gonococcal urethritis in men.

Authors:  R E Roddy; H H Handsfield; E W Hook
Journal:  Antimicrob Agents Chemother       Date:  1986-08       Impact factor: 5.191

Review 4.  Susceptibility testing of Chlamydia trachomatis: from eggs to monoclonal antibodies.

Authors:  J M Ehret; F N Judson
Journal:  Antimicrob Agents Chemother       Date:  1988-09       Impact factor: 5.191

5.  The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro.

Authors:  J S Wolfson; D C Hooper
Journal:  Antimicrob Agents Chemother       Date:  1985-10       Impact factor: 5.191

Review 6.  Quinolone antibacterial agents for the treatment of genitourinary tract infections.

Authors:  T J Babinchak; R J Fass
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-12       Impact factor: 3.267

7.  In vitro activities of temafloxacin (A-62254) and four other antibiotics against Chlamydia trachomatis.

Authors:  J Segreti; H A Kessler; K S Kapell; G M Trenholme
Journal:  Antimicrob Agents Chemother       Date:  1989-01       Impact factor: 5.191

8.  Determination of norfloxacin and ciprofloxacin concentrations in serum and urine by high-pressure liquid chromatography.

Authors:  S J Morton; V H Shull; J D Dick
Journal:  Antimicrob Agents Chemother       Date:  1986-08       Impact factor: 5.191

9.  Comparison of the in vitro activities of ofloxacin and tetracycline against Chlamydia trachomatis as assessed by indirect immunofluorescence.

Authors:  J M Bailey; C Heppleston; S J Richmond
Journal:  Antimicrob Agents Chemother       Date:  1984-07       Impact factor: 5.191

10.  Failure of norfloxacin to eradicate Chlamydia trachomatis in nongonococcal urethritis.

Authors:  W R Bowie; V Willetts; L Sibau
Journal:  Antimicrob Agents Chemother       Date:  1986-10       Impact factor: 5.191

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