| Literature DB >> 6228518 |
Abstract
There is good evidence to suggest that u.v. irradiation (UVB) of the skin causes a reduction in the numbers of normal epidermal Langerhans cells (LC) in man and mouse. Little information is available on the effects of u.v. radiation on LC in guinea-pig skin. In this study, different dosages of UVB and UVC were applied to the ear skin of guinea-pigs. UVC irradiations were found more effective than UVB in causing depletions of ATPase-positive epidermal LC. Highly significant depletions, lasting 6 days after irradiation, were produced with little evidence of significant inflammatory reactions occurring in the epidermis.Entities:
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Year: 1984 PMID: 6228518 PMCID: PMC1454408
Source DB: PubMed Journal: Immunology ISSN: 0019-2805 Impact factor: 7.397