Literature DB >> 6228486

[para-Aminobenzoic acid inhibits the manifestation of inducible SOS functions in Escherichia coli K-12].

S V Vasil'eva, T E Tonkal'.   

Abstract

In experiments with chemical mutagens (alkylating agents MNU, ENU, MMS and EMS), para-aminobenzoic acid (PABA) sharply inhibited the inducible processes in Escherichia coli, namely, mutagenesis, induction of lambda prophage and W-reactivation of UV-irradiated phage lambda. Based on experimental studies of E. coli strains deficient in different steps of DNA repair, the conclusion was made that PABA participates in regulation of the branch of DNA repair that is controlled by recA+ recF+ alleles.

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Year:  1983        PMID: 6228486

Source DB:  PubMed          Journal:  Genetika        ISSN: 0016-6758


  1 in total

1.  The role of p-aminobenzoic acid in DNA protection against oxidants.

Authors:  S V Vasil'eva; E V Makhova; E Y Moshkovskaya; G P Zhizhina
Journal:  Dokl Biol Sci       Date:  2000 Nov-Dec
  1 in total

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