Literature DB >> 622820

Anticore antibody screening of transfused blood.

J J Lander, G L Gitnick, L H Gelb, R D Aach.   

Abstract

Aliquots of 130 HB8Ag negative units of blood which were administered to 26 recipients were tested under code for anti-HBc by a solid phase radioimmunoassay technqiue. 14 of the 26 recipients developed posttransfusion hepatitis (PTH), including 6 cases of hepatitis B. Anti-HBc was detected in 7 or 5.3% of 130 donor units. Of the 14 patients acquiring PTH, 6 received a unit of anti-HBc-positive blood. Type B hepatitis occurred in 4 of the 7 anti-HBc recipients, and non-type B hepatitis in 2. Only 1 of 12 recipients who failed to develop PTH had received a unit containing anti-HBc.

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Year:  1978        PMID: 622820     DOI: 10.1111/j.1423-0410.1978.tb03726.x

Source DB:  PubMed          Journal:  Vox Sang        ISSN: 0042-9007            Impact factor:   2.144


  4 in total

Review 1.  Blood transfusion and hepatitis: still a threat?

Authors:  H W Reesink; C L van der Poel
Journal:  Blut       Date:  1989-01

2.  Serological evidence of presence of HBsAg undetectable by conventional radioimmunoassay in anti-HBc positive blood donors.

Authors:  J N Katchaki; T H Siem; R Brouwer
Journal:  J Clin Pathol       Date:  1978-09       Impact factor: 3.411

3.  The value of screening blood donors for antibody to hepatitis B core antigen.

Authors:  A C Archer; B J Cohen; P P Mortimer
Journal:  J Clin Pathol       Date:  1983-08       Impact factor: 3.411

4.  Anti-HBc screening for the prevention of perinatal transmission of hepatitis B virus in France.

Authors:  B Descos; J Scotto; V Fayol; J Y Huet; C Pichoud; M Hermier; G Ville; F Charvet; D Dargent; J M Thoulon
Journal:  Infection       Date:  1987 Nov-Dec       Impact factor: 3.553

  4 in total

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