Literature DB >> 6227667

Participation of auto-anti-idiotypes in immune complex glomerulonephritis in rabbits.

M Zanetti, C B Wilson.   

Abstract

We report the presence of auto-anti-Id antibodies in the glomerular immune deposits of a rabbit with chronic serum sickness induced by daily i.v. injections of bovine serum albumin. Auto-anti-Id antibodies were also documented in the serum of the same animal during the phase of chronic serum sickness in which immune complex glomerulonephritis develops. These results suggest that auto-anti-Id may normally participate in pathologic reactions and may be one of the mechanisms of potentiation and/or progression of immunopathologic lesions.

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Year:  1983        PMID： 6227667

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  5 in total

1.  Specificity and cross-reactive idiotypes of anti-gp330 autoantibodies in active Heymann nephritis.

Authors:  R J Specht Grijp-Glandorf; E De Heer; C C Dekker-Nooren; M R Daha; L A Van Es
Journal:  Immunology       Date:  1990-07       Impact factor: 7.397

Review 2.  Mechanisms of immune deposit formation in renal glomeruli.

Authors:  M H Wener; M Mannik
Journal:  Springer Semin Immunopathol       Date:  1986

3.  Characterization of circulating idiotypes containing immune complexes and their presence in the glomerular mesangium in patients with IgA nephropathy.

Authors:  J González-Cabrero; J Egido; F Mampaso; M C Rivas; L Hernando
Journal:  Clin Exp Immunol       Date:  1989-05       Impact factor: 4.330

4.  Precipitable immune complexes in healthy homosexual men, acquired immune deficiency syndrome and the related lymphadenopathy syndrome.

Authors:  H H Euler; P Kern; H Löffler; M Dietrich
Journal:  Clin Exp Immunol       Date:  1985-02       Impact factor: 4.330

5.  Active immunity against the CD4 receptor by using an antibody antigenized with residues 41-55 of the first extracellular domain.

Authors:  P Lanza; R Billetta; S Antonenko; M Zanetti
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-15       Impact factor: 11.205
  5 in total

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