Literature DB >> 6227497

Differential sensitivity to photohemolysis of erythrocytes enriched with some liposome-carried substances.

A Finazzi-Agrò, E Aquilio, C Crifò.   

Abstract

The sensitivity of human erythrocytes to photohemolysis sensitized by addition of protoporphyrin IX can be selectively affected by their enrichment with substances carried by cationic liposomes. In particular the enrichment which superoxide dismutase is accompanied by a copper-related greater sensitivity toward photohemolysis, as observed in the Down's syndrome (mongolism). Instead it is possible to protect the erythrocytes against the phototoxic effect of protoporphyrin by enrichment with small amounts of beta-carotene.

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Year:  1983        PMID: 6227497     DOI: 10.1007/bf01990379

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  19 in total

1.  Erythropoietic protoporphyria and lead intoxication: the molecular basis for difference in cutaneous photosensitivity. I. Different rates of disappearance of protoporphyrin from the erythrocytes, both in vivo and in vitro.

Authors:  S Piomelli; A A Lamola; M F Poh-Fitzpatrick; C Seaman; L C Harber
Journal:  J Clin Invest       Date:  1975-12       Impact factor: 14.808

2.  A pulse-radiolysis study of the manganese-containing superoxide dismutase from Bacillus stearothermophilus. A kinetic model for the enzyme action.

Authors:  M E McAdam; R A Fox; F Lavelle; E M Fielden
Journal:  Biochem J       Date:  1977-07-01       Impact factor: 3.857

3.  Superoxide dismutase in red blood cells: method of assay and enzyme content in normal subjects and in patients with beta-thalassemia (major and intermedia).

Authors:  A Concetti; P Massei; G Rotilio; M Brunori; E A Rachmilewitz
Journal:  J Lab Clin Med       Date:  1976-06

4.  Photodynamic therapy of malignant tumours.

Authors:  I Diamond; S G Granelli; A F McDonagh; S Nielsen; C B Wilson; R Jaenicke
Journal:  Lancet       Date:  1972-12-02       Impact factor: 79.321

5.  Cholesterol hydroperoxide formation in red cell membranes and photohemolysis in erythropoietic protoporphyria.

Authors:  A A Lamola; T Yamane; A M Trozzolo
Journal:  Science       Date:  1973-03-16       Impact factor: 47.728

6.  Protoporphyrin-sensitized photodynamic modification of proteins in isolated human red blood cell membranes.

Authors:  T M Dubbelman; A F de Goeij; J van Steveninck
Journal:  Photochem Photobiol       Date:  1978-08       Impact factor: 3.421

7.  Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine.

Authors:  J M Gutteridge; R Richmond; B Halliwell
Journal:  Biochem J       Date:  1979-11-15       Impact factor: 3.857

8.  Selective inactivation of catalase during protoporphyrin induced photohemolysis of human red blood cells.

Authors:  A Finazzi-Agrò; M B Fadda; G Floris; M R Dessi; C Crifò
Journal:  Experientia       Date:  1978-02-15

9.  The binding of copper ions to copper-free bovine superoxide dismutase. Copper distribution in protein samples recombined with less than stoicheiometric copper ion/protein ratios.

Authors:  A Rigo; P Viglino; L Calabrese; D Cocco; G Rotilio
Journal:  Biochem J       Date:  1977-01-01       Impact factor: 3.857

10.  Role of oxygen radicals scavenging enzymes in the protoporphyrin induced photohemolysis.

Authors:  A Finazzi-Agrò; G Floris; M B Fadda; C Crifò
Journal:  Experientia       Date:  1979-11-15
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