Literature DB >> 6226764

Nuclear membrane indentations in Huntington's chorea.

R A Roos, G T Bots.   

Abstract

Electron-microscopical examination of the nucleus accumbens, caudate nucleus and frontal cortex was performed in 21 patients with Huntington's disease (HD) and 21 age-matched controls. In HD, nuclear membrane indentations (NMI) were found in 25%, 29% and 20%, respectively, of the neurons of these areas. In the control group these figures were 4%, 4% and 38%, respectively. Possible pathogenetic mechanisms of the NMI are discussed.

Entities:  

Mesh：

Year:  1983        PMID： 6226764     DOI： 10.1016/0022-510x(83)90053-9

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN： 0022-510X            Impact factor:   3.181


  12 in total

1.  Neuronal distribution in the putamen in Huntington's disease.

Authors:  R A Roos; J F Pruyt; J de Vries; G T Bots
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-05       Impact factor: 10.154

2.  Attenuated nuclear shrinkage in neurones with nuclear inclusions of SCA1 brains.

Authors:  U Nagaoka; T Uchihara; K Iwabuchi; H Konno; M Tobita; N Funata; S Yagishita; T Kato
Journal:  J Neurol Neurosurg Psychiatry       Date:  2003-05       Impact factor: 10.154

3.  Temporal Characterization of Behavioral and Hippocampal Dysfunction in the YAC128 Mouse Model of Huntington's Disease.

Authors:  Cristine de Paula Nascimento-Castro; Elisa C Winkelmann-Duarte; Gianni Mancini; Priscilla Gomes Welter; Evelini Plácido; Marcelo Farina; Joana Gil-Mohapel; Ana Lúcia S Rodrigues; Andreza Fabro de Bem; Patricia S Brocardo
Journal:  Biomedicines       Date:  2022-06-17

4.  Huntington's disease is a four-repeat tauopathy with tau nuclear rods.

Authors:  Marta Fernández-Nogales; Jorge R Cabrera; María Santos-Galindo; Jeroen J M Hoozemans; Isidro Ferrer; Annemieke J M Rozemuller; Félix Hernández; Jesús Avila; José J Lucas
Journal:  Nat Med       Date:  2014-07-20       Impact factor: 53.440

5.  Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival.

Authors:  Caley J Burrus; Spencer U McKinstry; Namsoo Kim; M Ilcim Ozlu; Aditya V Santoki; Francia Y Fang; Annie Ma; Yonca B Karadeniz; Atesh K Worthington; Ioannis Dragatsis; Scott Zeitlin; Henry H Yin; Cagla Eroglu
Journal:  Cell Rep       Date:  2020-01-21       Impact factor: 9.423

Review 6.  Modeling Polyglutamine Expansion Diseases with Induced Pluripotent Stem Cells.

Authors:  Swati Naphade; Kizito-Tshitoko Tshilenge; Lisa M Ellerby
Journal:  Neurotherapeutics       Date:  2019-10       Impact factor: 7.620

7.  Manifestation of Huntington's disease pathology in human induced pluripotent stem cell-derived neurons.

Authors:  Evgeny D Nekrasov; Vladimir A Vigont; Sergey A Klyushnikov; Olga S Lebedeva; Ekaterina M Vassina; Alexandra N Bogomazova; Ilya V Chestkov; Tatiana A Semashko; Elena Kiseleva; Lyubov A Suldina; Pavel A Bobrovsky; Olga A Zimina; Maria A Ryazantseva; Anton Yu Skopin; Sergey N Illarioshkin; Elena V Kaznacheyeva; Maria A Lagarkova; Sergey L Kiselev
Journal:  Mol Neurodegener       Date:  2016-04-14       Impact factor: 14.195

8.  Delta Opioid Receptor Signaling Promotes Resilience to Stress Under the Repeated Social Defeat Paradigm in Mice.

Authors:  Mathilde S Henry; Kanchan Bisht; Nathalie Vernoux; Louis Gendron; Angélica Torres-Berrio; Guy Drolet; Marie-Ève Tremblay
Journal:  Front Mol Neurosci       Date:  2018-04-06       Impact factor: 5.639

9.  A translational murine model of sub-lethal intoxication with Shiga toxin 2 reveals novel ultrastructural findings in the brain striatum.

Authors:  Carla Tironi-Farinati; Patricia A Geoghegan; Adriana Cangelosi; Alipio Pinto; C Fabian Loidl; Jorge Goldstein
Journal:  PLoS One       Date:  2013-01-31       Impact factor: 3.240

10.  Introducing an expanded CAG tract into the huntingtin gene causes a wide spectrum of ultrastructural defects in cultured human cells.

Authors:  Ksenia N Morozova; Lyubov A Suldina; Tuyana B Malankhanova; Elena V Grigor'eva; Suren M Zakian; Elena Kiseleva; Anastasia A Malakhova
Journal:  PLoS One       Date:  2018-10-17       Impact factor: 3.240
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