Literature DB >> 6225824

Studies on the syngeneic mixed lymphocyte reaction. III. Development of a monoclonal antibody with specificity for autoreactive T cells.

P B Hausman, C E Moody, J B Innes, J J Gibbons, M E Weksler.   

Abstract

Monoclonal antibodies with specificity for autoreactive murine T cells have been developed. These antibodies inhibit proliferative response of splenic T cells activated by syngeneic spleen cells. These antibodies have no effect on the proliferative response of T cells activated by allogeneic spleen cells or PHA. The number of splenic T cells that react with these monoclonal antibodies is comparable in several normal mouse strains.

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Year:  1983        PMID： 6225824      PMCID： PMC2187364          DOI： 10.1084/jem.158.4.1307

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  21 in total

1.  A rapid method for the isolation of functional thymus-derived murine lymphocytes.

Authors:  M H Julius; E Simpson; L A Herzenberg
Journal:  Eur J Immunol       Date:  1973-10       Impact factor: 5.532

2.  Lymphocyte transformation induced by autologous cells. X. Soluble factors that generate cytotoxic T lymphocytes.

Authors:  M E Weksler; C E Moody; R F Ostry; B A Casazza
Journal:  J Exp Med       Date:  1980-08-01       Impact factor: 14.307

3.  The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease.

Authors:  L H Glimcher; A D Steinberg; S B House; I Green
Journal:  J Immunol       Date:  1980-10       Impact factor: 5.422

4.  T cells and macrophages involved in the autologous mixed lymphocyte reaction are required for the response to conventional antigen.

Authors:  P B Hausman; H V Raff; R C Gilbert; L J Picker; J D Stobo
Journal:  J Immunol       Date:  1980-09       Impact factor: 5.422

5.  Syngeneic mixed lymphocyte reaction in mice: strain distribution, kinetics, participating cells, and absence in NZB mice.

Authors:  J B Smith; R D Pasternak
Journal:  J Immunol       Date:  1978-11       Impact factor: 5.422

6.  The syngeneic mixed leukocyte reaction: the genetic requirements for the recognition of self resemble the requirements for the recognition of antigen in association with self.

Authors:  U Yamashita; E M Shevach
Journal:  J Immunol       Date:  1980-04       Impact factor: 5.422

7.  Lymphocyte transformation induced by autologous cells. V. Generation of immunologic memory and specificity during the autologous mixed lymphocyte reaction.

Authors:  M E Weksler; R Kozak
Journal:  J Exp Med       Date:  1977-12-01       Impact factor: 14.307

8.  Autologous stimulation of human lymphocyte subpopulation.

Authors:  G Opelz; M Kiuchi; M Takasugi; P I Terasaki
Journal:  J Exp Med       Date:  1975-11-01       Impact factor: 14.307

9.  Lymphocyte transformation induced by autologous cells. IV. Human T-lymphocyte proliferation induced by autologous or allogeneic non-T lymphocytes.

Authors:  M M Kuntz; J B Innes; M E Weksler
Journal:  J Exp Med       Date:  1976-05-01       Impact factor: 14.307

10.  Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells.

Authors:  H S Ko; S M Fu; R J Winchester; D T Yu; H G Kunkel
Journal:  J Exp Med       Date:  1979-08-01       Impact factor: 14.307
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  5 in total

1.  Maintenance of antigen specificity by human interleukin-2-dependent T cell lines. Use of antigen-presenting cells and OKT3 antibody in the absence of antigen.

Authors:  S J Padula; M K Pollard; E G Lingenheld; R B Clark
Journal:  J Clin Invest       Date:  1985-03       Impact factor: 14.808

Review 2.  Recognition of multiple class II signals by murine T cell antigen receptors. Speculation regarding the relationships among autoreactive, antigen-specific and alloreactive T cells.

Authors:  B W Needleman
Journal:  Immunol Res       Date:  1988       Impact factor: 2.829

3.  A role for self-recognizing T cells in the regulation of antibody-forming and cell-mediated cytotoxic responses in the mouse.

Authors:  R M Gorczynski; M Boulanger
Journal:  Immunology       Date:  1985-11       Impact factor: 7.397

4.  Ro/SSA inhibits the autologous mixed lymphocyte reaction.

Authors:  J Karsh; J B Harley; R Goldstein; A I Lazarovits
Journal:  Clin Exp Immunol       Date:  1993-01       Impact factor: 4.330

5.  Production of a cytokine with interleukin 3-like properties and cytokine-dependent proliferation in human autologous mixed lymphocyte reaction.

Authors:  R Suzuki; S Suzuki; T Takahashi; K Kumagai
Journal:  J Exp Med       Date:  1986-11-01       Impact factor: 14.307
  5 in total

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