| Literature DB >> 6225524 |
J Langhorne, F M Rollwagen, J F Finerty.
Abstract
Infection of C57BL/10 (B10)3 nu/nu mice with Trypanosoma rhodesiense results in the development of significant T-cell reactivity in spleen and lymph nodes. The proliferative responses to mitogens, such as concanavalin A (Con A) and phytohemagglutinin (PHA), and in mixed-lymphocyte reactions (MLR) to alloantigens are enhanced compared with control uninfected nu/nu mice. These results serve to emphasize the stimulatory nature of trypanosomes on the immune system.Entities:
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Year: 1983 PMID： 6225524 DOI： 10.1016/0008-8749(83)90224-1
Source DB: PubMed Journal: Cell Immunol ISSN： 0008-8749 Impact factor: 4.868