Literature DB >> 6225434

Ca2+/phospholipid-dependent protein kinase activity correlates to the ability of transformed liver cells to proliferate in Ca2+-deficient medium.

A L Boynton, J F Whitfield, L P Kleine.   

Abstract

Extracellular Ca2+-deprivation inhibited the proliferation of normal T51B rat liver cells and reduced (2-4 fold) the amount of EDTA/EGTA-extractable protein kinase C activity. By contrast, preneoplastic and neoplastic T51B rat liver cells were able to proliferate in Ca2+-deficient medium and retained all of their extractable protein kinase C activity.

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Year:  1983        PMID： 6225434     DOI： 10.1016/0006-291x(83)91015-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  5 in total

Review 1.  Calcium, cyclic AMP and protein kinase C--partners in mitogenesis.

Authors:  J F Whitfield; J P Durkin; D J Franks; L P Kleine; L Raptis; R H Rixon; M Sikorska; P R Walker
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

2.  The viral Ki-ras gene must be expressed in the G2 phase if ts Kirsten sarcoma virus-infected NRK cells are to proliferate in serum-free medium.

Authors:  J P Durkin; J F Whitfield
Journal:  Mol Cell Biol       Date:  1987-01       Impact factor: 4.272

3.  Characterization of G1 transit induced by the mitogenic-oncogenic viral Ki-ras gene product.

Authors:  J P Durkin; J F Whitfield
Journal:  Mol Cell Biol       Date:  1986-05       Impact factor: 4.272

4.  Reversible effect of calcium-binding protein regucalcin on the Ca(2+)-induced inhibition of deoxyuridine 5'-triphosphatase activity in rat liver cytosol.

Authors:  M Yamaguchi; T Sakurai
Journal:  Mol Cell Biochem       Date:  1992-03-04       Impact factor: 3.396

5.  Human papillomavirus type 31b late gene expression is regulated through protein kinase C-mediated changes in RNA processing.

Authors:  M Hummel; H B Lim; L A Laimins
Journal:  J Virol       Date:  1995-06       Impact factor: 5.103
  5 in total

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