Literature DB >> 6225037

Differential vulnerability of central neurons of the rat to quinolinic acid.

R Schwarcz, C Köhler.   

Abstract

Infusion of 120 nmol quinolinic acid into several regions of the rat's brain revealed differences in vulnerability to its neurotoxic effects, as judged by light microscopical analysis. The striatum, the pallidal formation and the hippocampus were the most susceptive brain areas whereas the cerebellum, substantia nigra, amygdala, medial septum and hypothalamus proved more resistant.

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Year:  1983        PMID: 6225037     DOI: 10.1016/0304-3940(83)90115-5

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


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