| Literature DB >> 6225024 |
Abstract
The Fusarium and Myrothecium mycotoxins roridin A, diacetoxyscirpenol, verrucarin A, T-2 toxin and zearalenone (10(-2) and 10(-3) mg/ml) inhibit the unspecific dehydrogenase activity of baker's yeast (Saccharomyces cerevisiae) in vivo. The action of these toxins is in the same order as that of aflatoxin B1. It is suggested that at least the trichothecenes decrease the dehydrogenase activity by an interaction with thiol groups of the active center of the enzymes.Entities:
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Year: 1983 PMID: 6225024 DOI: 10.1007/bf00436826
Source DB: PubMed Journal: Mycopathologia ISSN: 0301-486X Impact factor: 2.574