Literature DB >> 6223235

Subacute sclerosing panencephalitis: an immune complex disease?

A Sotrel, S Rosen, M Ronthal, D B Ross.   

Abstract

Vascular osmiophilic deposits of entangled tubular profiles were demonstrated by electronmicroscopy in the cerebral tissue of a patient with subacute sclerosing panencephalitis. Measles viral antigen, IgG, IgM, and C3 were found in the same distribution, indicating that the deposits represent immune complexes. To our knowledge, this is the first demonstration of immune complexes in the vessels of the central nervous system.

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Year:  1983        PMID: 6223235     DOI: 10.1212/wnl.33.7.885

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  2 in total

1.  A serum protein affecting the regulation of the immune system.

Authors:  D Karcher; A Lowenthal; P Stoppie; M Noppe
Journal:  Neurochem Res       Date:  1984-10       Impact factor: 3.996

Review 2.  Pathogenesis of virus-induced demyelination.

Authors:  J K Fazakerley; M J Buchmeier
Journal:  Adv Virus Res       Date:  1993       Impact factor: 9.937

  2 in total

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