Literature DB >> 62218

Activation of complement by the alternative pathway as a factor in the pathogenesis of periodontal disease.

A C Allison, H U Schorlemmer.   

Abstract

Dental plaque and a bacterium, Actinomyces viscosus, isolated from plaque that can reproduce periodontal disease in germ-free rats, are activators of complement by the alternative pathway. It is suggested that this process is involved in the pathogenesis of chronic inflammatory periodontal disease.

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Year:  1976        PMID: 62218     DOI: 10.1016/s0140-6736(76)90837-0

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  8 in total

1.  Some biological activities of Eikenella corrodens major outer membrane proteins.

Authors:  M A Tufano; L Sommese; F Galdiero
Journal:  Eur J Epidemiol       Date:  1986-12       Impact factor: 8.082

2.  Morphological features and functional properties of human fibroblasts exposed to Actinomyces viscosus substances.

Authors:  D Engel; H E Schroeder; R C Page
Journal:  Infect Immun       Date:  1978-01       Impact factor: 3.441

3.  Interaction of inflammatory cells and oral microorganisms. IV. In vitro release of lysosomal constituents from polymorphonuclear leukocytes exposed to supragingival and subgingival bacterial plaque.

Authors:  N S Taichman; C C Tsai; P C Baehni; N Stoller; W P McArthur
Journal:  Infect Immun       Date:  1977-06       Impact factor: 3.441

4.  Role of macrophages in the lymphocyte response to Actinomyces viscosus.

Authors:  R M McCarron; J E Fitzgerald; D C Birdsell
Journal:  Infect Immun       Date:  1982-11       Impact factor: 3.441

5.  The mechanism of basophil histamine release in patients with periodontal disease.

Authors:  A Olsson-Wennström; J L Wennström; S E Mergenhagen; R P Siraganian
Journal:  Clin Exp Immunol       Date:  1978-07       Impact factor: 4.330

Review 6.  Complement in immune and inflammatory disorders: pathophysiological mechanisms.

Authors:  Daniel Ricklin; John D Lambris
Journal:  J Immunol       Date:  2013-04-15       Impact factor: 5.422

7.  Dental caries and periodontal disease.

Authors:  T Lehner
Journal:  J R Soc Med       Date:  1978-03       Impact factor: 18.000

8.  Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates.

Authors:  Tetsuhiro Kajikawa; Ruel A Briones; Ranillo R G Resuello; Joel V Tuplano; Edimara S Reis; Evlambia Hajishengallis; Cristina A G Garcia; Despina Yancopoulou; John D Lambris; George Hajishengallis
Journal:  Mol Ther Methods Clin Dev       Date:  2017-08-18       Impact factor: 6.698

  8 in total

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