| Literature DB >> 6221758 |
D Pietrobon, M Zoratti, G F Azzone.
Abstract
The titration of the mitochondrial ATPase H+ pump with oligomycin has been compared with the titration of the redox H+ pump with antimycin. In both cases there is extensive inhibition of the pumps without significant depression of delta muH. The two pumps exhibit 'nonohmic' behavior in different ranges of delta muH. This discrepancy favors the hypothesis of nontightly coupled or 'slipping' H+ pumps with respect to that of a steep dependence of the membrane 'leak' conductance for H+ on delta muH.Entities:
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Year: 1983 PMID： 6221758 DOI： 10.1016/0005-2728(83)90131-7
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002