Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Identification of an I-J+ antigen-presenting cell required for third order suppressor cell activation.

Literature DB >> 6217280

Identification of an I-J+ antigen-presenting cell required for third order suppressor cell activation.

A Lowy, A Tominaga, J A Drebin, M Takaoki, B Benacerraf, M I Greene.

Abstract

We have found that an I-J+ I-A- antigen-presenting cell (APC) is required for Ts3 activation in vivo. Together with the I-J restriction previously reported for Ts3 induction (Takaoki, M., M.-S. Sy, A. Tominaga, A. Lowy, M. Tsurifiji, B. Benacerraf, R. Finberg, and M. I. Greene, 1982, J. Exp. Med., 156:1325), it appears that this I-J+ APC is responsible for I-J restriction in the triggering of Ts3. This restriction may be exerted via a pre-Ts3 associative recognition of antigen and I-J encoded determinants, analogous to the T helper recognition of antigen in the context of I-A and I-E determinants.

Entities: Disease

Mesh：

Substances：

Year: 1983 PMID： 6217280 PMCID： PMC2186903 DOI： 10.1084/jem.157.1.353

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

16 in total

1. Regulation of delayed-type hypersensitivity. III. Effect of cyclophosphamide on the suppressor cells for delayed-type hypersensitivity to sheep erythrocytes in mice.

Authors: H K Gill; F Y Liew
Journal: Eur J Immunol Date: 1978-03 Impact factor: 5.532

2. Mechanisms of regulation of cell-mediated immunity. II. Induction and suppression of delayed-type hypersensitivity to azobenzenearsonate-coupled syngeneic cells.

Authors: B A Bach; L Sherman; B Benacerraf; M I Greene
Journal: J Immunol Date: 1978-10 Impact factor: 5.422

3. Spontaneous remission and acquired resistance to autoimmune encephalomyelitis (EAE) are associated with suppression of T cell reactivity: suppressed EAE effector T cells recovered as T cell lines.

Authors: A Ben-Nun; I R Cohen
Journal: J Immunol Date: 1982-03 Impact factor: 5.422

Review 4. Helper and suppressor T cell factors.

Authors: R N Germain; B Benacerraf
Journal: Springer Semin Immunopathol Date: 1980-05

Review 5. Structural and serological properties of murine Ia alloantigens.

Authors: S E Cullen; J H Freed; S G Nathenson
Journal: Transplant Rev Date: 1976

6. Antigen- and receptor-driven regulatory mechanisms. IV. Idiotype-bearing I-J+ suppressor T cell factors induce second-order suppressor T cells which express anti-idiotypic receptors.

Authors: M S Sy; M H Dietz; R N Germain; B Benacerraf; M I Greene
Journal: J Exp Med Date: 1980-05-01 Impact factor: 14.307

7. The induction of cytolytic T lymphocytes with specificity for p-azophenylarsonate coupled syngeneic cells.

Authors: L A Sherman; S J Burakoff; B Benacerraf
Journal: J Immunol Date: 1978-10 Impact factor: 5.422

8. Regulation of the immune response to tumor antigens. III. Characterization of thymic suppressor factor(s) produced by tumor-bearing hosts.

Authors: M I Greene; S Fujimoto; A H Sehon
Journal: J Immunol Date: 1977-08 Impact factor: 5.422

9. Gene complementation in the T-lymphocyte proliferative response to poly (Glu55Lys36Phe9)n. A demonstration that both immune response gene products must be expressed in the same antigen-presenting cell.

Authors: R H Schwartz; A Yano; J H Stimpfling; W E Paul
Journal: J Exp Med Date: 1979-01-01 Impact factor: 14.307

10. Antigen- and receptor-driven regulatory mechanisms. III. Induction of delayed type hypersensitivity to azobenzenearsonate with anti-cross-reactive idiotypic antibodies.

Authors: M S Sy; A R Brown; B Benacerraf; M I Greene
Journal: J Exp Med Date: 1980-04-01 Impact factor: 14.307

15 in total

1. Cell-cell interaction responsible for the induction of first order suppressor T cells in hapten-specific contact sensitivity reactions.

Authors: Y Nakamura; R M Nakamura; T Tokunaga
Journal: Immunol Res Date: 1986 Impact factor: 2.829

2. Involvement of I-J epitopes in the self- and allo-recognition sites of T cells: blocking of syngeneic and allogeneic mixed lymphocyte reaction-responder cells by monoclonal anti-I-J antibodies.

Authors: W Uracz; R Abe; T Tada
Journal: Proc Natl Acad Sci U S A Date: 1985-05 Impact factor: 11.205

Identification of an I-J+ antigen-presenting cell required for third order suppressor cell activation.

1. Regulation of delayed-type hypersensitivity. III. Effect of cyclophosphamide on the suppressor cells for delayed-type hypersensitivity to sheep erythrocytes in mice.

2. Mechanisms of regulation of cell-mediated immunity. II. Induction and suppression of delayed-type hypersensitivity to azobenzenearsonate-coupled syngeneic cells.

3. Spontaneous remission and acquired resistance to autoimmune encephalomyelitis (EAE) are associated with suppression of T cell reactivity: suppressed EAE effector T cells recovered as T cell lines.

Review 4. Helper and suppressor T cell factors.

Review 5. Structural and serological properties of murine Ia alloantigens.

6. Antigen- and receptor-driven regulatory mechanisms. IV. Idiotype-bearing I-J+ suppressor T cell factors induce second-order suppressor T cells which express anti-idiotypic receptors.

7. The induction of cytolytic T lymphocytes with specificity for p-azophenylarsonate coupled syngeneic cells.

8. Regulation of the immune response to tumor antigens. III. Characterization of thymic suppressor factor(s) produced by tumor-bearing hosts.

9. Gene complementation in the T-lymphocyte proliferative response to poly (Glu55Lys36Phe9)n. A demonstration that both immune response gene products must be expressed in the same antigen-presenting cell.

10. Antigen- and receptor-driven regulatory mechanisms. III. Induction of delayed type hypersensitivity to azobenzenearsonate with anti-cross-reactive idiotypic antibodies.

1. Cell-cell interaction responsible for the induction of first order suppressor T cells in hapten-specific contact sensitivity reactions.

2. Involvement of I-J epitopes in the self- and allo-recognition sites of T cells: blocking of syngeneic and allogeneic mixed lymphocyte reaction-responder cells by monoclonal anti-I-J antibodies.

3. Visualization of anti-I-J antibody binding sites on bone marrow-derived macrophages.

4. Mannan as an antigen in cell-mediated immunity (CMI) assays and as a modulator of mannan-specific CMI.

5. Two types of suppressor T cells that inhibit delayed-type hypersensitivity to Mycobacterium intracellulare in mice.

6. Mechanism of regulation of immune responses by in vivo administration of monoclonal anti-I-A antibodies.

Review 7. Advances in the immunobiology of the skin. Implications for cutaneous malignancies.

8. I-J-positive cloned macrophages as accessory cells for the induction of suppressor T cells in vitro.

9. Accessory cell presentation of hapten-modified self.

10. Monocyte subsets in the production of inhibitory factor by Candida albicans-activated human T cells.