Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Influence of streptozotocin- and alloxan-induced diabetes on the crosslinking of dermal collagen.

Literature DB >> 6216710

Influence of streptozotocin- and alloxan-induced diabetes on the crosslinking of dermal collagen.

Abstract

The influence of experimentally induced diabetes on rat dermal collagen crosslinking was investigated in male albino rats. In comparison to the normal, the diabetic group demonstrated decrease in percent reversibility of neutral salt-soluble collagen gel and susceptibility of insoluble collagen to denaturing agents and pronase whereas the aldehyde content was significantly increased. The electrophoretic gels revealed a marked decrease of alpha/beta ratio in diabetic animals. The results indicated that both the intra- and intermolecular crosslinkings of collagen were increased in experimentally induced diabetes.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1982 PMID： 6216710 DOI： 10.1007/bf02624680

Source DB: PubMed Journal: Acta Diabetol Lat ISSN： 0001-5563

28 in total

5. Investigations on the reaction of metals with collagen in vivo. 2. The formation of cross-links in the collagen of lathyritic rats after gold treatment in vivo.

Authors: M Adam; P Fietzek; K Kühn
Journal: Eur J Biochem Date: 1968-02

6. Collagen cross-linking. Enzymatic synthesis of lysine-derived aldehydes and the production of cross-linked components.

Authors: R C Siegel; G R Martin
Journal: J Biol Chem Date: 1970-04-10 Impact factor: 5.157

7. In vivo and in vitro effects of alloxan on collagen characteristics of bone, skin and tendon of Swiss mice.

Authors: H N Behera; B K Patnaik
Journal: Gerontology Date: 1979 Impact factor: 5.140

8. Biosynthesis of collagen crosslinks: increased activity of purified lysyl oxidase with reconstituted collagen fibrils.

Authors: R C Siegel
Journal: Proc Natl Acad Sci U S A Date: 1974-12 Impact factor: 11.205

9. Effects of age and diabetes mellitus on the solubility and nonenzymatic glucosylation of human skin collagen.

Authors: S L Schnider; R R Kohn
Journal: J Clin Invest Date: 1981-06 Impact factor: 14.808

10. Influence of streptozotocin and alloxan induced diabetes on the metabolism of dermal collagen in albino rats.

Authors: S Mohanam; S Bose
Journal: Acta Diabetol Lat Date: 1981 Jul-Sep

1 in total

1. Influence of streptozotocin- and alloxan-induced diabetes in the rat on collagenase and certain lysosomal enzymes in relation to the degradation of connective tissue proteins.

Authors: S Mohanam; S M Bose
Journal: Diabetologia Date: 1983-07 Impact factor: 10.122

1 in total

Influence of streptozotocin- and alloxan-induced diabetes on the crosslinking of dermal collagen.

1. THE FORMATION AND DISSOLUTION OF GELS FROM COLLAGEN SOLUTIONS: THE EFFECT OF BETA-AMINOPROPIONITRILE.

2. Is diabetes a model for aging?

Review 3. Cross-linking amino acids in collagen and elastin.

4. Characterization of collagen peptides by sodium dodecylsulfate-polyacrylamide electrophoresis.