| Literature DB >> 6216479 |
F W Stahl, I Kobayashi, M M Stahl.
Abstract
Previous work showed that crossing-over in the middle of the chromosome of phage lambda requires more DNA replication than does crossing-over near the termini. Relocation of cos, the sequence that determines the lambda termini, alters the requirements for replication in a given marked interval, demonstrating that distance from cos determines the amount of DNA replication that is required for genetic exchange. This result supports a break and copy mechanism for recombination mediated by the red system of phage lambda.Entities:
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Year: 1982 PMID: 6216479 PMCID: PMC347112 DOI: 10.1073/pnas.79.20.6318
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205