Literature DB >> 6214237

[The usefulness of dexamethasonephosphate in the conservative treatment of lumbar pain--a double-blind study (author's transl)].

B Hofferberth, M Gottschaldt, H Grass, K Büttner.   

Abstract

Analgesic drugs, physiotherapy and corticosteroids are concurrently used in the conservative treatment of lumbar pain. In 100 patients a double-blind study with dexamethasonephosphate versus placebo was performed. Lumbar pain and no findings with myelography were the basic requirements for inclusion into the study. There was no significant difference between the treatment group and the placebo group concerning the clinical investigation before and after treatment. The positive effect of dexamethasonephosphate, which was seen in a pilot study, was not confirmed in the double-blind study. Because corticosteroids are also psychotropic drugs there is a mild antidepressive effect. Considering the fact that cortisone has no effect on the symptoms of lumbar pain, it should not be used furthermore in the conservative treatment of lumbar pain.

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Year:  1982        PMID: 6214237     DOI: 10.1007/bf00345591

Source DB:  PubMed          Journal:  Arch Psychiatr Nervenkr (1970)


  3 in total

1.  The lumbar disc herniation. A computer-aided analysis of 2,504 operations.

Authors:  E V Spangfort
Journal:  Acta Orthop Scand Suppl       Date:  1972

2.  The predictive value of myelography in the diagnosis of ruptured lumbar discs.

Authors:  W R Hudgins
Journal:  J Neurosurg       Date:  1970-02       Impact factor: 5.115

3.  Dexamethasone in the management of symptoms due to herniated lumbar disc.

Authors:  L N Green
Journal:  J Neurol Neurosurg Psychiatry       Date:  1975-12       Impact factor: 10.154

  3 in total
  3 in total

Review 1.  Imperfect placebos are common in low back pain trials: a systematic review of the literature.

Authors:  L A C Machado; S J Kamper; R D Herbert; C G Maher; J H McAuley
Journal:  Eur Spine J       Date:  2008-04-18       Impact factor: 3.134

Review 2.  Systemic corticosteroids for radicular and non-radicular low back pain.

Authors:  Roger Chou; Rafael Zambelli Pinto; Rongwei Fu; Robert A Lowe; Nicholas Henschke; James H McAuley; Tracy Dana
Journal:  Cochrane Database Syst Rev       Date:  2022-10-21

Review 3.  Drugs for relief of pain in patients with sciatica: systematic review and meta-analysis.

Authors:  Rafael Zambelli Pinto; Chris G Maher; Manuela L Ferreira; Paulo H Ferreira; Mark Hancock; Vinicius C Oliveira; Andrew J McLachlan; Bart Koes
Journal:  BMJ       Date:  2012-02-13
  3 in total

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