| Literature DB >> 6213789 |
Abstract
The biological activity of heads of bacteriophages phi 80 and lambda in in vitro assembly with tails was inhibited by dialysis, filtration on gels, and treatment with tryptamine. Inhibition by these three treatments could be prevented but not reversed by putrescine. Other diamines with shorter or longer carbon chain lengths were either less effective or not effective at all. It is suggested that tryptamine acts by loosening the tightly packed DNA in heads, whereas putrescine stabilizes it.Entities:
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Year: 1982 PMID： 6213789 PMCID： PMC256180
Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103