Literature DB >> 6212257

Suppression of T cell responses through competition for T cell growth factor (interleukin 2).

J Günther, W Haas, H Von Boehmer.   

Abstract

Addition of activated T cells or of cells from a cytotoxic T cell clone to mixed leukocyte cultures abolished the generation of cytolytic activity in these cultures. The cytolytic T cell response is completely restored if T cell growth factor (interleukin 2) is added, indicating that the suppression is due to absorption or consumption of IL2 by the added cells.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6212257     DOI： 10.1002/eji.1830120315

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  16 in total

1.  Competition for antigenic sites during T cell proliferation: a mathematical interpretation of in vitro data.

Authors:  J A Borghans; L S Taams; M H Wauben; R J de Boer
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-14       Impact factor: 11.205

2.  In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro.

Authors:  Ludger Klein; Khashayarsha Khazaie; Harald von Boehmer
Journal:  Proc Natl Acad Sci U S A       Date:  2003-07-11       Impact factor: 11.205

3.  Influenza peptide-induced self-lysis and down-regulation of cloned cytotoxic T cells.

Authors:  R M Pemberton; D C Wraith; B A Askonas
Journal:  Immunology       Date:  1990-06       Impact factor: 7.397

4.  Kinetics of purified protein derivative (PPD) proliferation reflects underlying suppressor mechanisms revealed by limiting dilution analysis (LDA) in patients with extrapulmonary tuberculosis (TB).

Authors:  P T Lukey; S E Latouf; S R Ress
Journal:  Clin Exp Immunol       Date:  1998-02       Impact factor: 4.330

5.  Selective in-vitro activation of BALB/c T suppressor lymphocytes specific for syngeneic ADJ-PC-5 plasmacytoma cells.

Authors:  H D Haubeck; I Minkenberg; E Kölsch
Journal:  Clin Exp Immunol       Date:  1988-10       Impact factor: 4.330

6.  Oral polio vaccine influences the immune response to BCG vaccination. A natural experiment.

Authors:  Erliyani Sartono; Ida M Lisse; Elisabeth M Terveer; Paula J M van de Sande; Hilton Whittle; Ane B Fisker; Adam Roth; Peter Aaby; Maria Yazdanbakhsh; Christine S Benn
Journal:  PLoS One       Date:  2010-05-21       Impact factor: 3.240

7.  Activity of CD4+ T-cell clones of type 1 and type 2 in generation of influenza virus-specific cytotoxic responses in vitro.

Authors:  G Palladino; P A Scherle; W Gerhard
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

8.  Paradoxical presence of T cell anergy during successful T cell-dependent tumour immunotherapy: characterization of a state of T cell 'amnaesia' following systemic administration of C. parvum.

Authors:  W H McBride; S Howie
Journal:  Clin Exp Immunol       Date:  1984-07       Impact factor: 4.330

9.  Suppressive mechanisms in alloantigen-induced T cell responses.

Authors:  M Beckwith; S Rich
Journal:  J Exp Med       Date:  1983-12-01       Impact factor: 14.307

10.  Impairment of T cell activation in burn patients: a possible mechanism of thermal injury-induced immunosuppression.

Authors:  J A Teodorczyk-Injeyan; B G Sparkes; G B Mills; W J Peters; R E Falk
Journal:  Clin Exp Immunol       Date:  1986-09       Impact factor: 4.330
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.