Literature DB >> 6211188

Oxytetracycline in the treatment of ocular rosacea: a double-blind trial.

R S Bartholomew, B J Reid, M J Cheesbrough, M Macdonald, N R Galloway.   

Abstract

Thirty-five patients with ocular rosacea were admitted to a trial of systemic oxytetracycline, 250 mg b.d. for 6 weeks. Oxytetracycline produced a significantly higher number of remissions than the placebo, 11/35. With repeated or continuous treatment 19/35 patients achieved a sustained remission for 8 months. There were no side effects. The nonspecific signs of ocular rosacea responded well to the treatment, but no permanent change in the conjunctival or corneal vascularisation occurred.

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Year:  1982        PMID： 6211188      PMCID： PMC1039805          DOI： 10.1136/bjo.66.6.386

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN： 0007-1161            Impact factor:   4.638


  9 in total

1.  Ocular rosacea.

Authors:  M S Jenkins; S I Brown; S L Lempert; R J Weinberg
Journal:  Am J Ophthalmol       Date:  1979-09       Impact factor: 5.258

2.  Diagnosis and treatment of ocular rosacea.

Authors:  S I Brown; L Shahinian
Journal:  Ophthalmology       Date:  1978-08       Impact factor: 12.079

3.  Tetracyclines in the treatment of ocular rosacea.

Authors:  V J Marmion
Journal:  Proc R Soc Med       Date:  1969-01

4.  A clinical trial of tetracycline in rosacea.

Authors:  I B Sneddon
Journal:  Br J Dermatol       Date:  1966-12       Impact factor: 9.302

5.  The ocular aspects of rosacea.

Authors:  M J Roper-Hall
Journal:  Trans Ophthalmol Soc U K       Date:  1966

6.  Comparative effectiveness of tetracycline and ampicillin in rosacea. A controlled trial.

Authors:  R Marks; J Ellis
Journal:  Lancet       Date:  1971-11-13       Impact factor: 79.321

7.  Complications of tetracycline therapy for acne.

Authors:  R S Gilgor
Journal:  N C Med J       Date:  1972-04

8.  The long-term use of tetracycline in acne vulgaris: effect on blood elements.

Authors:  L S Osment; W J Hammack
Journal:  South Med J       Date:  1970-10       Impact factor: 0.954

9.  Effects of long term treatment with tetracycline.

Authors:  T J Delaney; B J Leppard; D M MacDonald
Journal:  Acta Derm Venereol       Date:  1974       Impact factor: 4.437
  9 in total
  6 in total

Review 1.  Interventions for chronic blepharitis.

Authors:  Kristina Lindsley; Sueko Matsumura; Elham Hatef; Esen K Akpek
Journal:  Cochrane Database Syst Rev       Date:  2012-05-16

Review 2.  Dry eye disease: an immune-mediated ocular surface disorder.

Authors:  William Stevenson; Sunil K Chauhan; Reza Dana
Journal:  Arch Ophthalmol       Date:  2012-01

Review 3.  Interventions for rosacea.

Authors:  Esther J van Zuuren; Zbys Fedorowicz; Ben Carter; Mireille M D van der Linden; Lyn Charland
Journal:  Cochrane Database Syst Rev       Date:  2015-04-28

4.  Placebo controlled trial of fusidic acid gel and oxytetracycline for recurrent blepharitis and rosacea.

Authors:  D V Seal; P Wright; L Ficker; K Hagan; M Troski; P Menday
Journal:  Br J Ophthalmol       Date:  1995-01       Impact factor: 4.638

5.  Oral antibiotics for chronic blepharitis.

Authors:  Neil Onghanseng; Sueko M Ng; Muhammad Sohail Halim; Quan Dong Nguyen
Journal:  Cochrane Database Syst Rev       Date:  2021-06-09

6.  Expert opinion in the management of aqueous Deficient Dry Eye Disease (DED).

Authors:  Aileen Sy; Kieran S O'Brien; Margaret P Liu; Puja A Cuddapah; Nisha R Acharya; Thomas M Lietman; Jennifer Rose-Nussbaumer
Journal:  BMC Ophthalmol       Date:  2015-10-13       Impact factor: 2.209
  6 in total

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