Literature DB >> 621088

A silent gene (C3-) producing partial deficiency of the third component of human complement.

H H Hoppe, H W Goedde, D P Agarwal, L Hirth, W Janssen.   

Abstract

A family is described with 3 members in 3 generations being heterozygous for the silent gene C3-: one girl, her mother and grandfather had half normal C3 levels and were apparently incompatible homozygous. No significant deviation in the total hemolytic complement activity, serum concentration of Bf and C4 component was found in the affected individuals.

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Year:  1978        PMID: 621088     DOI: 10.1159/000152954

Source DB:  PubMed          Journal:  Hum Hered        ISSN: 0001-5652            Impact factor:   0.444


  3 in total

1.  [Use of DNA polymorphism in forensic paternity evaluation].

Authors:  L Henke; H Paas; K Hoffmann; J Henke
Journal:  Z Rechtsmed       Date:  1990

2.  A rare phenotype C3, F-F0.8 encountered in three successive generations of one family.

Authors:  C Brandt-Casadevall; N Dimo-Simonin; H R Gujer
Journal:  Z Rechtsmed       Date:  1983

3.  DNA-minisatellite mutations: recent investigations concerning distribution and impact on parentage testing.

Authors:  J Henke; R Fimmers; M P Baur; L Henke
Journal:  Int J Legal Med       Date:  1993       Impact factor: 2.686

  3 in total

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