Literature DB >> 6210356

Anti-inflammatory action of drugs that raise adenosine-3',5'-cyclic monophosphate and putrescine levels in-vivo.

S Mohd Hidir, D A Lewis.   

Abstract

Isoprenaline and salbutamol, two beta-adrenoceptor agonist drugs, and 3-isobutyl-methyl xanthine and thioacetamide have been shown to be anti-inflammatory. Their mode of action is probably due to an increase in the levels of the three endogenous substances adenosine-3',5'-cyclic monophosphate and putrescine and spermidine in-vivo.

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Year:  1984        PMID: 6210356     DOI: 10.1111/j.2042-7158.1984.tb04867.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  2 in total

1.  Modification by some antagonists of the shape changes of venous endothelial cells in response to inflammatory agents in vitro.

Authors:  A M Northover
Journal:  Agents Actions       Date:  1990-03

2.  Polyamines in rat liver during experimental inflammation.

Authors:  S Colombatto; L Fasulo; M A Grillo
Journal:  Agents Actions       Date:  1988-07
  2 in total

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