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Literature DB >> 6210210

Intracerebroventricular injection of cerebrospinal fluid (CSF) from a patient with congenital indifference to pain induces analgesia in rats.

A Fabbri, F Fraioli, G Cruccu, M Manfredi, C B Pert, A Pert.

Abstract

CSF from a patient with congenital indifference to pain was found to produce analgesia in the rat following intracerebroventricular injections. The analgesic effect was attenuated by pretreatment with naloxone suggesting the involvement of hyperactive endogenous opiate mechanisms in this patient.

Entities: Chemical Disease Species

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Year: 1984 PMID： 6210210 DOI： 10.1007/bf01951891

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

11 in total

1. Lack of opiate receptor involvement in centrally induced calcitonin analgesia.

Authors: P Braga; S Ferri; A Santagostino; V R Olgiati; A Pecile
Journal: Life Sci Date: 1978-03 Impact factor: 5.037

2. Autosomal dominant insensitivity to pain with hyperplastic myelinopathy and autosomal dominant indifference to pain.

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Journal: Neurology Date: 1974-09 Impact factor: 9.910

3. Is calcitonin an analgesic hormone?

Authors: A Fabbri; F Fraioli; L Gnessi; C Moretti; G Bini; G Cruccu; M Manfredi
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4. Failure of naloxone to reverse analgesia in congenital insensitivity to pain, and variable plasma levels of beta-endorphin-like activity.

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Journal: Lancet Date: 1982-03-13 Impact factor: 79.321

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Journal: Peptides Date: 1982 Nov-Dec Impact factor: 3.750

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Journal: Horm Metab Res Date: 1982-06 Impact factor: 2.936

7. Subarachnoid injection of salmon calcitonin induces analgesia in man.

Authors: F Fraioli; A Fabbri; L Gnessi; C Moretti; C Santoro; M Felici
Journal: Eur J Pharmacol Date: 1982-03-12 Impact factor: 4.432

8. Bombesin: receptor distribution in brain and effects on nociception and locomotor activity.

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Journal: Brain Res Date: 1980-07-07 Impact factor: 3.252

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Authors: M Manfredi; G Bini; G Cruccu; N Accornero; A Berardelli; L Medolago
Journal: Arch Neurol Date: 1981-08

10. Effect of naloxone in a previously undescribed hypothalamic syndrome. A disorder of the endogenous opioid peptide system?

Authors: D B Dunger; J V Leonard; O H Wolff; M A Preece
Journal: Lancet Date: 1980-06-14 Impact factor: 79.321

2 in total

1. Peak B endorphin concentration in cerebrospinal fluid: reduced in chronic pain patients and increased during the placebo response.

Authors: J J Lipman; B E Miller; K S Mays; M N Miller; W C North; W L Byrne
Journal: Psychopharmacology (Berl) Date: 1990 Impact factor: 4.530

2. A central mechanism of analgesia in mice and humans lacking the sodium channel Na_V1.7.

Authors: Donald Iain MacDonald; Shafaq Sikandar; Jan Weiss; Martina Pyrski; Ana P Luiz; Queensta Millet; Edward C Emery; Flavia Mancini; Gian D Iannetti; Sascha R A Alles; Manuel Arcangeletti; Jing Zhao; James J Cox; Robert M Brownstone; Frank Zufall; John N Wood
Journal: Neuron Date: 2021-04-05 Impact factor: 17.173

2 in total