Literature DB >> 6208907

1,10-Phenanthroline reversibility inhibits proliferation of two human prostate carcinoma cell lines (PC-3 and DU145).

J L Ware, D F Paulson, K S Webb.   

Abstract

The metal chelator 1,10-phenanthroline reversibly inhibits proliferation of two human prostate carcinoma cell lines, PC-3 and DU145. Inhibition is dose-dependent, and persists for several days after removal of the chelator. The ability to induce reversible quiescence in human prostate carcinoma cells in vitro may facilitate the study of their growth cycle biochemistry.

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Year:  1984        PMID： 6208907     DOI： 10.1016/0006-291x(84)91587-0

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  3 in total

1.  Effects of iron chelators, iron salts, and iron oxide nanoparticles on the proliferation and the iron content of oligodendroglial OLN-93 cells.

Authors:  Michaela Hohnholt; Mark Geppert; Ralf Dringen
Journal:  Neurochem Res       Date:  2010-05-14       Impact factor: 3.996

2.  Iron reverses impermeable chelator inhibition of DNA synthesis in CCl 39 cells.

Authors:  F J Alcain; H Löw; F L Crane
Journal:  Proc Natl Acad Sci U S A       Date:  1994-08-16       Impact factor: 11.205

3.  Sulfur inhibits the growth of androgen-independent prostate cancer in vivo.

Authors:  Fei Duan; Yuhua Li; Liangkang Chen; Xiaoyu Zhou; Jianxing Chen; Hailin Chen; Runsheng Li
Journal:  Oncol Lett       Date:  2014-11-11       Impact factor: 2.967
  3 in total

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