Xerodermoid induced by photochemotherapy.

Photochemotherapy induces alterations in the skin that resemble those in xeroderma pigmentosum. Acute responses may be distinguished from late, chronic, and delayed responses to PUVA. All of the types of cells present in the skin are affected by photochemotherapy. The structure of the epidermis and of the superficial dermis are altered and, possibly as a consequence, neoplasms may ensue.