Literature DB >> 6208633

A cytotoxic anti-HLA-AB monoclonal antibody which in dilution becomes specific to HLA-A3 crossreacting group.

M C Mazzilli, I Cascino, S C Porrini, M V Lavaggi, P Lulli, M Morellini, L Testa, E Gandini.   

Abstract

XI 20.4 monoclonal antibody belongs to the IgM class. It precipitates two polypeptide chains characteristic of HLA Class I antigens. At the highest dilutions it is cytotoxic against lymphocytes carrying antigens of the HLA-A3 crossreacting group. Lysostrip experiments show that, at the lowest dilutions, the antibody reacts either with HLA-A, or B antigens.

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Year:  1984        PMID: 6208633     DOI: 10.1111/j.1399-0039.1984.tb02113.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN: 0001-2815


  1 in total

1.  Mapping of A3 and A2 polymorphic determinants on hybrid HLA antigens.

Authors:  B Kahn-Perles; J Sire; A Toubert; C Layet; R Hakem; P Pontarotti; R Sodoyer; B R Jordan; F A Lemonnier
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

  1 in total

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