Literature DB >> 6208158

Sertoli-Leydig cell tumor of the ovary producing alpha-fetoprotein.

J C Chumas, Z Rosenwaks, W J Mann, G Finkel, J Pastore.   

Abstract

A 16-year-old girl with virilization and elevated serum alpha-fetoprotein (AFP) levels was found to have a Sertoli-Leydig cell tumor of the ovary. Immunoperoxidase studies using anti-AFP localized AFP in cells with the histologic appearance of Leydig cells. Serum AFP fell to undetectable levels after excision of the tumor. The patient is alive and well 1 year postexcision.

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Year:  1984        PMID: 6208158     DOI: 10.1097/00004347-198402000-00009

Source DB:  PubMed          Journal:  Int J Gynecol Pathol        ISSN: 0277-1691            Impact factor:   2.762


  5 in total

Review 1.  Ovarian Sertoli-Leydig cell tumor with heterologous elements of gastrointestinal type associated with elevated serum alpha-fetoprotein level: an unusual case and literature review.

Authors:  Mariana Horta; Teresa Margarida Cunha; Rita Canas Marques; Ana Félix
Journal:  J Radiol Case Rep       Date:  2014-11-30

2.  Immunohistochemistry of ovarian granulosa cell tumours. The value of tissue specific proteins and tumour markers.

Authors:  S Chadha; T H van der Kwast
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

3.  15-Year-Old Patient with an Unusual Alpha-Fetoprotein-Producing Sertoli-Leydig Cell Tumor of Ovary.

Authors:  Kaçar Serife; Stavros Karampelas; Nathalie Hottat; Christine Devalck; Katherina Vanden Houte
Journal:  Case Rep Obstet Gynecol       Date:  2022-04-12

4.  Ovarian Sertoli-Leydig cell tumour with raised serum alpha fetoprotein. A case report.

Authors:  A Tiltman; K Dehaeck; R Soeters; G Goldberg; W Levin
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

5.  Immunohistochemical type distinction of alpha-fetoprotein in various alpha-fetoprotein-secreting tumors.

Authors:  T Okamoto; K Hirabayashi; T Ishiguro
Journal:  Jpn J Cancer Res       Date:  1993-04
  5 in total

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