Literature DB >> 6207849

The stimulatory effects of caffeine, theophylline, lysine-theophylline and 3-isobutyl-1-methylxanthine on human sperm motility.

C S Jiang, S A Kilfeather, R M Pearson, P Turner.   

Abstract

The potencies of caffeine, theophylline, lysine-theophylline and 3-isobutyl-1-methylxanthine (IBMX) in stimulating sperm motility have been compared, and we have found IBMX to be significantly more potent than the other three compounds, which did not exhibit significant differences in potency from each other.

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Year:  1984        PMID： 6207849      PMCID： PMC1463533          DOI： 10.1111/j.1365-2125.1984.tb02466.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  26 in total

1.  Congenital malformations in offspring of mice treated with caffeine.

Authors:  H NISHIMURA; K NAKAI
Journal:  Proc Soc Exp Biol Med       Date:  1960-05

2.  Induction of motility in immature bovine spermatozoa by cyclic AMP phosphodiesterase inhibitors and seminal plasma.

Authors:  D D Hoskins; M L Hall; D Munsterman
Journal:  Biol Reprod       Date:  1975-09       Impact factor: 4.285

3.  Effect of two phosphodiesterase inhibitors, cyclic adenosine 3':5'-monophosphate, and a beta-blocking agent on human sperm motility.

Authors:  E De Turner; N J Aparicio; D Turner; L Schwarzstein
Journal:  Fertil Steril       Date:  1978-03       Impact factor: 7.329

4.  Ionic effects on the motility of bull and chimpanzee spermatozoa.

Authors:  A V McGrady; L Nelson; M Ireland
Journal:  J Reprod Fertil       Date:  1974-09

Review 5.  The regulation of spermatozoa by calcium cyclic nucleotides.

Authors:  D L Garbers; G S Kopf
Journal:  Adv Cyclic Nucleotide Res       Date:  1980

6.  The pharmacokinetics of lysine theophylline, a new soluble theophylline, in human volunteers.

Authors:  A Johnston; M E Aldhous; A Hedges; K Weerasuriya; A Freedman; P Turner
Journal:  Postgrad Med J       Date:  1983-02       Impact factor: 2.401

7.  A simple method to measure drug effects on human sperm motility.

Authors:  C Y Hong; D M Chaput de Saintonge; P Turner
Journal:  Br J Clin Pharmacol       Date:  1981-04       Impact factor: 4.335

8.  On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors.

Authors:  B B Fredholm; K Brodin; K Strandberg
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1979-11

9.  Effect of caffeine on the motility, viability, oxygen consumption and glycolytic rate of ejaculated human normokinetic and hypokinetic spermatozoa.

Authors:  Z T Homonnai; G Paz; A Sofer; P F Kraicer; A Harell
Journal:  Int J Fertil       Date:  1976

10.  Human sperm motility--enhancement and inhibition measured by laser Doppler spectroscopy.

Authors:  R Hartmann; R Steiner; N Hofmann; R Kaufmann
Journal:  Andrologia       Date:  1983 Mar-Apr       Impact factor: 2.775
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  9 in total

1.  Involvement of calcium in the caffeine stimulation of human sperm motility.

Authors:  C Y Hong; B N Chiang; P Wu; Y H Wei; J C Fong
Journal:  Br J Clin Pharmacol       Date:  1985-06       Impact factor: 4.335

2.  A modified trans-membrane migration method for measuring the effect of drugs on sperm motility.

Authors:  N T Raoof; R M Pearson; P Turner
Journal:  Br J Clin Pharmacol       Date:  1987-09       Impact factor: 4.335

Review 3.  The effects of drugs on sperm.

Authors:  J O Drife
Journal:  Drugs       Date:  1987-06       Impact factor: 9.546

Review 4.  Clinical pharmacology of Cilomilast.

Authors:  Geoff Down; Sarah Siederer; Sam Lim; Peter Daley-Yates
Journal:  Clin Pharmacokinet       Date:  2006       Impact factor: 6.447

Review 5.  Current Insights and Latest Updates in Sperm Motility and Associated Applications in Assisted Reproduction.

Authors:  Reyon Dcunha; Reda S Hussein; Hanumappa Ananda; Sandhya Kumari; Satish Kumar Adiga; Nagarajan Kannan; Yulian Zhao; Guruprasad Kalthur
Journal:  Reprod Sci       Date:  2020-12-07       Impact factor: 3.060

Review 6.  Recent observations on drugs and human fertility.

Authors:  P Turner
Journal:  Postgrad Med J       Date:  1988-08       Impact factor: 2.401

Review 7.  Respiratory Cilia as a Therapeutic Target of Phosphodiesterase Inhibitors.

Authors:  Marta Joskova; Juraj Mokry; Sona Franova
Journal:  Front Pharmacol       Date:  2020-05-06       Impact factor: 5.810

Review 8.  Signaling Enzymes Required for Sperm Maturation and Fertilization in Mammals.

Authors:  Souvik Dey; Cameron Brothag; Srinivasan Vijayaraghavan
Journal:  Front Cell Dev Biol       Date:  2019-12-18

9.  Quinoline Derivative Enhances Human Sperm Motility and Improves the Functional Competence.

Authors:  Sandhya Kumari; Sujith Raj Salian; Arpitha Rao; Shilpa M Somagond; Ravindra R Kamble; Aravind Nesaragi; Jyotirekha Das; G K Rajanikant; Srinivas Mutalik; Shamprasad Varija Raghu; Satish Kumar Adiga; Guruprasad Kalthur
Journal:  Reprod Sci       Date:  2020-11-25       Impact factor: 3.060
  9 in total

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