Literature DB >> 620748

Different effects of synthetic delta 9-tetrahydrocannabinol and cannabis extract on steroid metabolism in male rats.

M P Maskarinec, G Shipley, M Novotny, D J Brown, R B Forney.   

Abstract

Repeated oral administration of cannabis extract as well as synthetic delta9-tetrahydrocannabinol to male rats produced significant changes in excretion of androgenic steroids and their metabolites as detectable in blood and urine. Cannabis extracts were found to be significantly more active than the mixtures containing same amounts of synthetic cannabinoids.

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Year:  1978        PMID: 620748     DOI: 10.1007/bf01921920

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  14 in total

1.  High-resolution gas chromatography of plasma steroidal hormones and their metabolites.

Authors:  M Novotny; M P Maskarinec; A T Steverink; R Farlow
Journal:  Anal Chem       Date:  1976-03       Impact factor: 6.986

2.  Cannabis demasculinizes rats but is not estrogenic.

Authors:  A B Okey; G S Truant
Journal:  Life Sci       Date:  1975-10-10       Impact factor: 5.037

3.  Metabolism of testosterone sulfate in the rat: analysis of biliary metabolites.

Authors:  M Matsui; Y Kinuyama; M Hakozaki
Journal:  Steroids       Date:  1975-05       Impact factor: 2.668

4.  Plasma testosterone and dihydrotestosterone in male rats during sexual maturation and following orchidectomy and experimental bilateral cryptorchidism.

Authors:  D Gupta; J Zarzycki; K Rager
Journal:  Steroids       Date:  1975-01       Impact factor: 2.668

5.  Distribution of tritiated-1 delta 9tetrahydrocannabinol in rat tissues after inhalation.

Authors:  B T Ho; G E Fritchie; P M Kralik; L F Englert; W M McIsaac; J Idänpään-Heikkilä
Journal:  J Pharm Pharmacol       Date:  1970-07       Impact factor: 3.765

6.  Reduction in copulatory behavior of male rats following hashish injections.

Authors:  M E Corcoran; Z Amit; C W Malsbury; S Daykin
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1974-04

7.  Depression of plasma testosterone levels after chronic intensive marihuana use.

Authors:  R C Kolodny; W H Masters; R M Kolodner; G Toro
Journal:  N Engl J Med       Date:  1974-04-18       Impact factor: 91.245

8.  Chronic oral toxicity of cannabinoids in rats.

Authors:  G R Thompson; M M Mason; H Rosenkrantz; M C Braude
Journal:  Toxicol Appl Pharmacol       Date:  1973-07       Impact factor: 4.219

9.  Effects of 1(2) -tetrahydrocannabinol on copulation in the male rat.

Authors:  A Merari; A Barak; M Plaves
Journal:  Psychopharmacologia       Date:  1973

10.  Gynecomastia in marihuana users.

Authors:  J Harmon; M A Aliapoulios
Journal:  N Engl J Med       Date:  1972-11-02       Impact factor: 91.245

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