Literature DB >> 620739

A tonic component in the motility of the upper urinary tract (renal pelvis-ureter).

K Golenhofen, J Hannappel.   

Abstract

In isolated muscle strips of porcine renal pelvis and ureter, the calcium antagonist nifedipine (3.10(-7) moles/l) completely suppressed spontaneous phasic mechanical activity and the phasic components of an adrenaline-induced activation (P-component). In the presence of nifedipine, adrenaline induced in pelvis preparations (but not in the ureter) a tonic contraction (T-component) which was on average 61% of the control reaction (SD +/- 26%; n = 35).

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Year:  1978        PMID: 620739     DOI: 10.1007/bf01921904

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  1 in total

1.  The effect of catecholamines on ureteral peristalsis in different species (dog, guinea-pigs and rat).

Authors:  J Hannappel; K Golenhofen
Journal:  Pflugers Arch       Date:  1974       Impact factor: 3.657

  1 in total
  1 in total

1.  Structure-activity studies on nifedipine in isolated cardiac muscle.

Authors:  R Rodenkirchen; R Bayer; R Steiner; F Bossert; H Meyer; E Möller
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-12       Impact factor: 3.000

  1 in total

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