Literature DB >> 6207270

Amino acid uptake by dorsal root ganglia from streptozotocin-diabetic rats.

P K Thomas, D W Wright, E Tzebelikos.   

Abstract

Dorsal root ganglia from streptozotocin-diabetic rats and age- and weight-matched control animals were incubated with 4-amino 3H-butyric acid. A significant reduction in uptake was observed in the diabetic animals. The incorporation of 3H-leucine into protein was also significantly reduced but the results did not allow a conclusion as to whether this was a secondary or an independent effect. These findings are discussed in relation both to the abnormalities known to develop in diabetic rats and to the causation of human diabetic neuropathy.

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Year:  1984        PMID： 6207270      PMCID： PMC1027990          DOI： 10.1136/jnnp.47.9.912

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  25 in total

1.  Diminished ouabain-sensitive, sodium-potassium ATPase activity in sciatic nerves of rats with streptozotocin-induced diabetes.

Authors:  P K Das; G M Bray; A J Aguayo; M Rasminsky
Journal:  Exp Neurol       Date:  1976-10       Impact factor: 5.330

2.  Amino acid incorporation in protein during the "silent phase" before organo-mercury and p-bromophenylacetylurea neuropathy in the rat.

Authors:  J B Cavanagh; F C Chen
Journal:  Acta Neuropathol       Date:  1971       Impact factor: 17.088

3.  Anabolic responses of embryonic dorsal root ganglia to nerve growth factor, insulin, concanavalin A or serum in vitro.

Authors:  P A Burnham; J A Silva; S Varon
Journal:  J Neurochem       Date:  1974-10       Impact factor: 5.372

4.  Mechanism of cycloheximide inhibition of protein synthesis in a cell-free system prepared from rat liver.

Authors:  B S Baliga; A W Pronczuk; H N Munro
Journal:  J Biol Chem       Date:  1969-08-25       Impact factor: 5.157

5.  Axonal transport in early experimental diabetes.

Authors:  P Sidenius; J Jakobsen
Journal:  Brain Res       Date:  1979-09-14       Impact factor: 3.252

6.  Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes.

Authors:  D A Greene; P V De Jesus; A I Winegrad
Journal:  J Clin Invest       Date:  1975-06       Impact factor: 14.808

7.  Metabolism of peripheral nerve myelin in experimental diabetes.

Authors:  N Spritz; H Singh; B Marinan
Journal:  J Clin Invest       Date:  1975-05       Impact factor: 14.808

8.  Free and lipid myo-inositol in tissues from rats with acute and less severe streptozotocin-induced diabetes.

Authors:  K P Palmano; P H Whiting; J N Hawthorne
Journal:  Biochem J       Date:  1977-10-01       Impact factor: 3.857

9.  Reduced perikaryal volume of lower motor and primary sensory neurons in early experimental diabetes.

Authors:  P Sidenius; J Jakobsen
Journal:  Diabetes       Date:  1980-03       Impact factor: 9.461

10.  Early and preventable changes of peripheral nerve structure and function in insulin-deficient diabetic rats.

Authors:  J Jakobsen
Journal:  J Neurol Neurosurg Psychiatry       Date:  1979-06       Impact factor: 10.154
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  11 in total

Review 1.  Neurology.

Authors:  A N Gale; J M Gibbs; A H Schapira; P K Thomas
Journal:  Postgrad Med J       Date:  1991-06       Impact factor: 2.401

2.  Sodium-potassium-ATPase activity in the dorsal root ganglia of rats with streptozotocin-induced diabetes.

Authors:  R J Green; R H King; P K Thomas; D N Baron
Journal:  Diabetologia       Date:  1985-02       Impact factor: 10.122

3.  A defect in sodium-dependent amino acid uptake in diabetic rabbit peripheral nerve. Correction by an aldose reductase inhibitor or myo-inositol administration.

Authors:  D A Greene; S A Lattimer; P B Carroll; J D Fernstrom; D N Finegold
Journal:  J Clin Invest       Date:  1990-05       Impact factor: 14.808

4.  Aldose reductase in the BB rat: isolation, immunological identification and localization in the retina and peripheral nerve.

Authors:  S Chakrabarti; A A Sima; T Nakajima; S Yagihashi; D A Greene
Journal:  Diabetologia       Date:  1987-04       Impact factor: 10.122

5.  Changes in sorbitol, myo-inositol and lipid inositol in dorsal root and sympathetic ganglia from streptozotocin-diabetic rats.

Authors:  J G Llewelyn; C M Simpson; P K Thomas; R H King; J N Hawthorne
Journal:  Diabetologia       Date:  1986-12       Impact factor: 10.122

6.  Impaired prosaposin secretion during nerve regeneration in diabetic rats and protection of nerve regeneration by a prosaposin-derived peptide.

Authors:  Corinne G Jolivalt; Yvonne Vu; Leah M Mizisin; Andrew P Mizisin; Nigel A Calcutt
Journal:  J Neuropathol Exp Neurol       Date:  2008-07       Impact factor: 3.685

7.  Peripheral nerve intramembranous particle density and distribution in chronic streptozotocin-induced diabetes in rats.

Authors:  G Gabriel; P K Thomas; R H King; C Stolinski; A S Breathnach
Journal:  Acta Neuropathol       Date:  1986       Impact factor: 17.088

8.  Beneficial effects and mechanism of action of Momordica charantia juice in the treatment of streptozotocin-induced diabetes mellitus in rat.

Authors:  I Ahmed; E Adeghate; E Cummings; A K Sharma; J Singh
Journal:  Mol Cell Biochem       Date:  2004-06       Impact factor: 3.396

9.  Leucocyte sodium efflux and electrolyte content in insulin treated diabetes.

Authors:  L L Ng; D Simmons; M Harker; T D Hockaday
Journal:  Diabetologia       Date:  1988-11       Impact factor: 10.122

10.  The effects of dietary treatment with essential fatty acids on sciatic nerve conduction and activity of the Na+/K+ pump in streptozotocin-diabetic rats.

Authors:  M J Lockett; D R Tomlinson
Journal:  Br J Pharmacol       Date:  1992-02       Impact factor: 8.739
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