Literature DB >> 620718

DNA-dependent-DNA-polymerase: possible limiting influence on cell reproduction during viral leukemogenesis.

J P Okunewick, P G Braunschweiger.   

Abstract

Evidence is presented that during viral leukemogenesis spleen cell nuclei show an increase in labelling index and mean grain count, that is not accompanied by any changes in the nuclear level of DNA-polymerase-alpha. It is suggested that polymerase production remains under the control of the normal cell mechanisms and the virus may affect cell proliferation by altering the primer-template levels.

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Year:  1978        PMID： 620718     DOI： 10.1007/bf01921932

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  15 in total

1.  GROWTH CURVE OF A MURINE LEUKEMIA VIRUS IN MICE.

Authors:  F J RAUSCHER; B V ALLEN
Journal:  J Natl Cancer Inst       Date:  1964-02       Impact factor: 13.506

2.  Murine leukemia virus: detection of unintegrated double-stranded DNA forms of the provirus.

Authors:  A M Gianni; D Smotkin; R A Weinberg
Journal:  Proc Natl Acad Sci U S A       Date:  1975-02       Impact factor: 11.205

3.  Antiserum inactivation of hematopoietic colony forming stem cells from mice with Rauscher leukemia.

Authors:  J P Okunewick; E L Phillips; B J Brozovich
Journal:  Experientia       Date:  1974-12-15

4.  The presence of unique DNA sequences after viral induction of leukemia in mice. (RNA tumor virus-nucleic acid hybridization-insertion of viral DNA).

Authors:  R W Sweet; N C Goodman; J R Cho; R M Ruprecht; R R Redfield; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

5.  Cycling characteristics of human lymphocytes in vitro.

Authors:  L M Schiffer; A M Markoe; A Winkelstein; J S Nelson; J M Mikulla
Journal:  Blood       Date:  1974-07       Impact factor: 22.113

6.  Growth rate and 59 Fe uptake in the progeny of Rauscher leukemia virus-infected splenic colony forming units following transplantation.

Authors:  J P Okunewick; A M Markoe; P Erhard; E L Phillips
Journal:  J Lab Clin Med       Date:  1973-04

7.  The haematopoietic stem cell in Rauscher virus-induced erythroblastosis of BALB/c mice.

Authors:  E J Brommer; P Bentvelzen
Journal:  Eur J Cancer       Date:  1974-12       Impact factor: 9.162

8.  Sulfhydryl groups and estradiol-receptor interaction.

Authors:  E V Jensen; D J Hurst; E R DeSombre; P W Jungblut
Journal:  Science       Date:  1967-10-20       Impact factor: 47.728

9.  [Hemopoietic stem cells in murine viurs-induced leukemia. I. Spleen colony assays in CBA mice after Rauscher virus infection (author's transl)].

Authors:  H J Seidel
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1973

10.  Estimation of tumor growth fraction in murine tumors by the primer-available DNA-dependent DNA polymerase assay.

Authors:  L M Schiffer; A M Markoe; J S Nelson
Journal:  Cancer Res       Date:  1976-07       Impact factor: 12.701
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