Do infiltrative and anaplastic growth patterns alternate with season in human breast cancer?

The presence/absence of stromal metachromasia, at the zone of host-tumour interaction, was recorded in 220 primary breast carcinomas. This reaction, which is associated with an infiltrative as opposed to an expansive growth form, was more common in primaries removed in the first half of the year than the second. This adds to previous evidence based on histological grading that growth synchronization has occurred in breast carcinomas in this district.