Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The source of the dispersity of gramicidin A single-channel conductances. The L X Leu5-gramicidin A analog.

Literature DB >> 6206902

The source of the dispersity of gramicidin A single-channel conductances. The L X Leu5-gramicidin A analog.

D W Urry, S Alonso-Romanowski, C M Venkatachalam, T L Trapane, K U Prasad.

Abstract

The L X Leu5-gramicidin A analog has been designed, synthesized, and verified for the purpose of testing the perspective that different side-chain distributions are responsible for the dispersity of single-channel conductances. The structural analysis shows that the L . Leu5 analog would limit the possible number of side-chain distributions and that the dispersity of channel conductances would decrease. The finding is the expected decrease in less probable conductance states and the associated increase in the probability of the most probable conductance state.

Entities: Chemical

Mesh：

Substances：

Year: 1984 PMID： 6206902 PMCID： PMC1435031 DOI： 10.1016/S0006-3495(84)84019-9

Source DB: PubMed Journal: Biophys J ISSN： 0006-3495 Impact factor: 4.033

19 in total

1. A 13C nuclear magnetic resonance study of gramicidin A in monomer and dimer forms.

Authors: E T Fossel; W R Veatch; U A Ovchinnikov; E R Blout
Journal: Biochemistry Date: 1974-12-17 Impact factor: 3.162

2. The malonyl gramicidin channel: NMR-derived rate constants and comparison of calculated and experimental single-channel currents.

Authors: D W Urry; C M Venkatachalam; A Spisni; R J Bradley; T L Trapane; K U Prasad
Journal: J Membr Biol Date: 1980-06-30 Impact factor: 1.843

3. Synthetic peptide K+ carrier with Ca2+ inhibition.

Authors: R J Bradley; W O Romine; M M Long; T Onishi; M A Jacobs; D W Urry
Journal: Arch Biochem Biophys Date: 1977-01-30 Impact factor: 4.013

4. Ion movement through gramicidin A channels. Single-channel measurements at very high potentials.

Authors: O S Andersen
Journal: Biophys J Date: 1983-02 Impact factor: 4.033

5. Gramicidin forms multi-state rectifying channels.

Authors: D Busath; G Szabo
Journal: Nature Date: 1981-11-26 Impact factor: 49.962

6. Single-channel parameters of gramicidin A,B, and C.

Authors: E Bamberg; K Noda; E Gross; P Läuger
Journal: Biochim Biophys Acta Date: 1976-01-21

7. Location of monovalent cation binding sites in the gramicidin channel.

Authors: D W Urry; K U Prasad; T L Trapane
Journal: Proc Natl Acad Sci U S A Date: 1982-01 Impact factor: 11.205

8. Rate theory calculation of gramicidin single-channel currents using NMR-derived rate constants.

Authors: D W Urry; C M Venkatachalam; A Spisni; P Läuger; M A Khaled
Journal: Proc Natl Acad Sci U S A Date: 1980-04 Impact factor: 11.205

9. Structure of the gramicidin A channel: discrimination between the piL,D and the beta helix by electrical measurements with lipid bilayer membranes.

Authors: E Bamberg; H J Apell; H Alpes
Journal: Proc Natl Acad Sci U S A Date: 1977-06 Impact factor: 11.205

10. Is the gramicidin a transmembrane channel single-stranded or double-stranded helix? A simple unequivocal determination.

Authors: D W Urry; T L Trapane; K U Prasad
Journal: Science Date: 1983-09-09 Impact factor: 47.728

7 in total

1. Open channel noise. V. Fluctuating barriers to ion entry in gramicidin A channels.

Authors: S H Heinemann; F J Sigworth
Journal: Biophys J Date: 1990-03 Impact factor: 4.033

2. On the conductance heterogeneity in membrane channels formed by gramicidin A. A cooperative study.

Authors: D D Busath; O S Andersen; R E Koeppe
Journal: Biophys J Date: 1987-01 Impact factor: 4.033

3. Open channel noise. III. High-resolution recordings show rapid current fluctuations in gramicidin A and four chemical analogues.

Authors: F J Sigworth; D W Urry; K U Prasad
Journal: Biophys J Date: 1987-12 Impact factor: 4.033