Literature DB >> 6206729

The ultrastructural localization of keratin proteins and carcinoembryonic antigen in malignant mesotheliomas.

M J Warhol.   

Abstract

The immunoultrastructural localization of keratin proteins and carcinoembryonic antigen (CEA) in mesothelioma cells was accomplished with a low-temperature embedding colloidal gold technique. The keratin antiserum labeled only intermediate filaments. These filaments surrounded the cytoplasmic organelles and were inserted into desmosomes. The CEA antiserum labeled cytoplasmic vesicles and droplets. No definite labeling of microvilli was observed.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6206729      PMCID： PMC1900476     

Source DB:  PubMed          Journal:  Am J Pathol        ISSN： 0002-9440            Impact factor:   4.307


  9 in total

1.  Electron microscopy in the diagnosis of pleural mesotheliomas.

Authors:  N S Wang
Journal:  Cancer       Date:  1973-05       Impact factor: 6.860

2.  Intermediate filaments.

Authors:  M Osborn; N Geisler; G Shaw; G Sharp; K Weber
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1982

3.  Applications of immunocolloids in light microscopy. Preparation of protein A-silver and protein A-gold complexes and their application for localization of single and multiple antigens in paraffin sections.

Authors:  J Roth
Journal:  J Histochem Cytochem       Date:  1982-07       Impact factor: 2.479

4.  Intermediate filaments as mechanical integrators of cellular space.

Authors:  E Lazarides
Journal:  Nature       Date:  1980-01-17       Impact factor: 49.962

5.  Ultrastructural localization of carcinoembryonic antigen in normal intestine and colon cancer: abnormal distribution of CEA on the surfaces of colon cancer cells.

Authors:  D J Ahnen; P K Nakane; W R Brown
Journal:  Cancer       Date:  1982-05-15       Impact factor: 6.860

6.  Malignant mesothelioma: ultrastructural distinction from adenocarcinoma.

Authors:  M J Warhol; W F Hickey; J M Corson
Journal:  Am J Surg Pathol       Date:  1982-06       Impact factor: 6.394

7.  Mesothelioma: profile of keratin proteins and carcinoembryonic antigen: an immunoperoxidase study of 20 cases and comparison with pulmonary adenocarcinomas.

Authors:  J M Corson; G S Pinkus
Journal:  Am J Pathol       Date:  1982-07       Impact factor: 4.307

8.  Ultrastructure of human malignant diffuse mesothelioma.

Authors:  Y Suzuki; M Kannerstein
Journal:  Am J Pathol       Date:  1976-11       Impact factor: 4.307

9.  Immunohistochemical localization of prekeratin filaments in benign and malignant cells in effusions. Comparison with intermediate filament distribution by electron microscopy.

Authors:  H J Kahn; W Hanna; H Yeger; R Baumal
Journal:  Am J Pathol       Date:  1982-11       Impact factor: 4.307
  9 in total
  2 in total

1.  Neuropathy in IgM lambda paraproteinemia. Immunoreactivity to neural proteins and chondroitin sulfate.

Authors:  W C Yee; A F Hahn; S A Hearn; A R Rupar
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

2.  The intermediate filament cytoskeleton of malignant mesotheliomas and its diagnostic significance.

Authors:  G A Blobel; R Moll; W W Franke; K W Kayser; V E Gould
Journal:  Am J Pathol       Date:  1985-11       Impact factor: 4.307
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.