Literature DB >> 6205929

Functional analogs of bleomycin: sequence-specific DNA cleavage with porphyrin (Fe) intercalators.

Y Hashimoto, H Iijima, K Shudo.   

Abstract

Synthetic porphyrin (Fe) intercalators cleave DNA at guanine-cytosine and guanine-thymine sequences. The specificity for cleavage of base sequences of DNA is quite similar to that of bleomycin.

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Year:  1984        PMID: 6205929

Source DB:  PubMed          Journal:  Gan        ISSN: 0016-450X


  1 in total

1.  Sequence-targeted chemical modifications of nucleic acids by complementary oligonucleotides covalently linked to porphyrins.

Authors:  L Perrouault; M Chassignol; T T Nguyen; C Hélène
Journal:  Nucleic Acids Res       Date:  1987-11-11       Impact factor: 16.971

  1 in total

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