Literature DB >> 6205893

Differential sensitivity to ethidium bromide of replicative DNA synthesis and bleomycin-induced unscheduled DNA synthesis in permeable mouse sarcoma cells.

S Seki, T Oda.   

Abstract

Replicative DNA synthesis in permeable mouse sarcoma cells was more sensitive to ethidium bromide (EtBr) than bleomycin-induced unscheduled DNA synthesis (UDS). A similar difference in sensitivity to EtBr was observed between DNA polymerases alpha and beta. The difference in sensitivity to EtBr of replicative DNA synthesis and UDS in the present system seems to reflect mainly the sensitivity difference between DNA polymerases alpha and beta.

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Year:  1984        PMID: 6205893     DOI: 10.1007/bf01952001

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  18 in total

1.  DNA polymerase of mitochondria is a gamma-polymerase.

Authors:  A Bolden; G P Noy; A Weissbach
Journal:  J Biol Chem       Date:  1977-05-25       Impact factor: 5.157

2.  Differential effects of heparin on replicative DNA synthesis and unscheduled DNA synthesis.

Authors:  S Seki; T Oda
Journal:  Biochim Biophys Acta       Date:  1977-12-14

3.  Dissociation and reconstitution of the DNA replicase system of HeLa cell nuclei.

Authors:  S Seki; G C Mueller
Journal:  Biochim Biophys Acta       Date:  1976-07-02

4.  Low molecular weight deoxyribonucleic acid polymerase from calf thymus chromatin. I. Preparation of homogeneous enzyme.

Authors:  L M Chang
Journal:  J Biol Chem       Date:  1973-06-10       Impact factor: 5.157

5.  Binding of ethidium bromide to avian erythrocyte chromatin.

Authors:  P F Lurquin; V L Seligy
Journal:  Biochem Biophys Res Commun       Date:  1972-02-16       Impact factor: 3.575

6.  DNA biosynthesis in mitochondria. Differential inhibition of mitochondrial and nuclear DNA polymerases by the mutagenic dyes ethidium bromide and acriflavin.

Authors:  R R Meyer; M V Simpson
Journal:  Biochem Biophys Res Commun       Date:  1969-01-27       Impact factor: 3.575

7.  Mitochondrial DNA polymerase from rat liver.

Authors:  T Fujisawa; S Tanaka; M Kobayashi; K Koike
Journal:  Biochim Biophys Acta       Date:  1977-04-19

8.  Inhibition of replicative DNA synthesis and induction of unscheduled DNA synthesis in permeable sarcoma cell by bleomycin.

Authors:  S Seki; T Oda
Journal:  Biochim Biophys Acta       Date:  1978-12-21

9.  Inhibition of hepatitis B DNA polymerase by intercalating agents.

Authors:  S Z Hirschman; E Garfinkel
Journal:  Nature       Date:  1978-02-16       Impact factor: 49.962

10.  Differential effects of aphidicolin on replicative DNA synthesis and unscheduled DNA synthesis in permeable mouse sarcoma cells.

Authors:  S Seki; T Oda; M Ohashi
Journal:  Biochim Biophys Acta       Date:  1980-12-11
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  1 in total

1.  Inhibition of O6-alkylguanine-DNA alkyltransferase and DNase I activities in vitro by some alkylating substances and antineoplastic agents.

Authors:  A Link; K Tempel
Journal:  J Cancer Res Clin Oncol       Date:  1991       Impact factor: 4.553

  1 in total

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