Sleep-wakefulness patterns in the aged cat.

This investigation compared the 24 h sleep-wake characteristics of young adult (2-4 years) and old (10-11 years) cats in order to determine whether there were significant age- and/or gender-related differences. Aged animals had more brief (6-14 sec) awakenings, less REM sleep, and more NREM sleep than young adults. There were no significant age- or gender-related differences with respect to either the daily numbers or the mean durations of sleep and waking episodes. Compared with the young adults, aged males had substantially less DSWS and fewer numbers of short-duration (less than or equal to 2.5 min) LSWS bouts. Both males and females showed age-related differences with respect to the sequencing of state-patterns. The expression of these patterns in relation to time of day was comparable for young and old animals. Overall, these findings compare favorably with those commonly reported in the elderly human.