Literature DB >> 6204935

Action of lysosomotropic amines on spontaneous and interferon enhanced NK and CTL cytolysis.

C Ausiello, V Sorrentino, V Ruggiero, G B Rossi.   

Abstract

Cell-mediated cytotoxicities, such as natural killer (NK) and T-dependent cytotoxic (CTL) activities, are inhibited to the same extent by lysosomotropic amines, even when interferon is added to cultures to enhance lysis. It is postulated that the amines block steps common to spontaneous and IFN-enhanced NK and CTL lytic mechanisms.

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Year:  1984        PMID： 6204935     DOI： 10.1016/0165-2478(84)90097-x

Source DB:  PubMed          Journal:  Immunol Lett        ISSN： 0165-2478            Impact factor:   3.685


  2 in total

1.  Cell-mediated cytotoxicity in glioma-bearing patients: differential responses of peripheral blood mononuclear cells to stimulation with interleukin-2 and microbial antigen.

Authors:  C Ausiello; A Maleci; G C Spagnoli; G Antonelli; A Cassone
Journal:  J Neurooncol       Date:  1988-12       Impact factor: 4.130

2.  Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1.

Authors:  Anneliese O Speak; Danielle Te Vruchte; Lianne C Davis; Anthony J Morgan; David A Smith; Nicole M Yanjanin; Louise Simmons; Ralf Hartung; Heiko Runz; Eugen Mengel; Michael Beck; Jackie Imrie; Elizabeth Jacklin; James E Wraith; Christian Hendriksz; Robin Lachmann; Celine Cognet; Rohini Sidhu; Hideji Fujiwara; Daniel S Ory; Antony Galione; Forbes D Porter; Eric Vivier; Frances M Platt
Journal:  Blood       Date:  2013-11-14       Impact factor: 22.113
  2 in total

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