Literature DB >> 6204890

Islet-activating protein, pertussis toxin, inhibits Ca2+-induced and guanine nucleotide-dependent releases of histamine and arachidonic acid from rat mast cells.

T Nakamura, M Ui.   

Abstract

Islet-activating protein (IAP) suppressed Ca2+-induced histamine release and phospholipase A2 activation in Gpp(NH)p-loaded mast cells. Since the guanine nucleotide-binding protein involved in adenylate cyclase inhibition is known to lose its function upon being ADP-ribosylated by IAP, the nucleotide-binding protein is likely to mediate Ca2+-linked biosignalling leading to histamine secretion.

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Year:  1984        PMID： 6204890     DOI： 10.1016/0014-5793(84)80816-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  15 in total

1.  Role of guanine nucleotide-binding protein in the regulation by adenosine of cardiac potassium conductance and force of contraction. Evaluation with pertussis toxin.

Authors:  M Böhm; R Brückner; J Neumann; W Schmitz; H Scholz; J Starbatty
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-04       Impact factor: 3.000

2.  [Cardiac effects of adenosine. Mechanism of action, pathophysiologic and clinical significance].

Authors:  M Böhm
Journal:  Klin Wochenschr       Date:  1987-06-01

Review 3.  G protein regulation of phospholipase A2.

Authors:  R M Burch
Journal:  Mol Neurobiol       Date:  1989       Impact factor: 5.590

4.  Effect of protein kinase C inhibitor (H-7) and calmodulin antagonist (W-7) on pertussis toxin-induced IL-1 production by human adherent monocytes. Comparison with lipopolysaccharide as a stimulator of IL-1 production.

Authors:  H Taniguchi; T Sakano; T Hamasaki; H Kashiwa; K Ueda
Journal:  Immunology       Date:  1989-06       Impact factor: 7.397

5.  Thyroliberin action in pituitary cells is not inhibited by pertussis toxin.

Authors:  P M Hinkle; E L Hewlett; M C Gershengorn
Journal:  Biochem J       Date:  1986-07-01       Impact factor: 3.857

6.  Evidence suggesting that a novel guanine nucleotide regulatory protein couples receptors to phospholipase C in exocrine pancreas.

Authors:  J E Merritt; C W Taylor; R P Rubin; J W Putney
Journal:  Biochem J       Date:  1986-06-01       Impact factor: 3.857

7.  Pertussis toxin inhibits chemotactic peptide-stimulated generation of inositol phosphates and lysosomal enzyme secretion in human leukemic (HL-60) cells.

Authors:  S J Brandt; R W Dougherty; E G Lapetina; J E Niedel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

8.  Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: role of G proteins in excitation response coupling.

Authors:  M Volpi; P H Naccache; T F Molski; J Shefcyk; C K Huang; M L Marsh; J Munoz; E L Becker; R I Sha'afi
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

9.  Further evidence that muscarinic cholinergic receptors of 1321N1 astrocytoma cells couple to a guanine nucleotide regulatory protein that is not Ni.

Authors:  M W Martin; T Evans; T K Harden
Journal:  Biochem J       Date:  1985-07-15       Impact factor: 3.857

10.  The inhibition of neutrophil granule enzyme secretion and chemotaxis by pertussis toxin.

Authors:  E L Becker; J C Kermode; P H Naccache; R Yassin; M L Marsh; J J Munoz; R I Sha'afi
Journal:  J Cell Biol       Date:  1985-05       Impact factor: 10.539
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